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Details for Product No. ABIN114914

Prolactin-Induced Protein (PIP) antibody

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Antigen
Synonyms GPIP4, GCDFP15, GCDFP-15, GP17, mSMGP
Reactivity
»Alternatives Human, Rat (Rattus)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Pubmed 2 references available
Catalog no. ABIN114914
Quantity 0.5 mL
Price
275.00 $   Plus shipping costs $45.00
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Immunogen Recombinant protein encoding the excreted domain of human GCDFP-15
Clone 23A3
Isotype IgG2a
Specificity This antibody is specific to 15 kD monomer protein called Gross Cystic Disease Fluid Protein-15 (GCDFP-15). Gross cystic disease of the breast is benign premenopausal disorder in which cysts are predominant. These cysts appear to be formed from excessive apocrine cystic secretions, one of which is GCDFP-15. This antibody can be used in for the staining of breast carcinoma, salivary duct carcinoma and apocrine epithelia. Cellular localization: Cytoplasmic.
Purification Supernatant
Alternative Name PIP / GCDFP15
Background Gross Cystic Disease Fluid Protein-15 (GCDFP-15) is a 15 kD monomer protein. Gross cystic disease of the breast is benign premenopausal disorder in which cysts are predominant. These cysts appear to be formed from excessive apocrine cystic secretions, one of which is GCDFP-15.
Alternate names: GCDFP-15, GPIP4, Gross cystic disease fluid protein 15, Prolactin-induced protein, Prolactin- inducible protein, SABP, Secretory actin-binding protein, gp17
Gene ID 5304
NCBI Accession NP_002643.1
UniProt P12273
Application Notes Immunohistochemistry: 1/10-1/20 in an ABC method. Incubation period: 60 minutes atroom temperature. Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Skin. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month. DO NOT FREEZE!
Expiry Date 12 months
Viacava, Naccarato, Bevilacqua: "Spectrum of GCDFP-15 expression in human fetal and adult normal tissues." in: Virchows Archiv : an international journal of pathology, Vol. 432, Issue 3, pp. 255-60, 1998 (PubMed).

Hall, Clements, Birrell et al.: "Prostate-specific antigen and gross cystic disease fluid protein-15 are co-expressed in androgen receptor-positive breast tumours." in: British journal of cancer, Vol. 78, Issue 3, pp. 360-5, 1998 (PubMed).

Alternatives for antigen "Prolactin-Induced Protein (PIP)", type "Antibodies"
Hosts (56), (21), (10)
Reactivities (57), (16), (12), (12), (1)
Applications (45), (32), (30), (26), (11), (6), (6), (6), (4), (2), (1), (1)
Conjugates (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (7), (4), (2), (2), (2), (1)
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