Cytokeratin 5 (KRT5) antibody
| Antigen |
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| Synonyms |
KRT79, CK5, KRT5, K5, Tfip8, Krt2-5, AW146334, 3300001P10Rik, DDD, EBS2, KRT5A |
| Clonality |
Monoclonal (XM26) |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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| Catalog no. |
ABIN115171 |
| Quantity |
1 ml (Variants) |
| Price |
440.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: KRT5, Cytokeratin-5, Keratin-5, Keratin 5, CK5, K5, Keratin type II cytoskeletal 5, 58 kDaCytokeratin
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Alternative name
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Cytokeratin 5
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Swiss-Prot
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P13647
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Immunogen
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Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-terminalregion of the human Cytokeratin 5 molecule
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Format
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Supernatant
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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XM26
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Description
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Basal cells of human epidermis express acidic Cytokeratin 14 and basic Cytokeratin 5. Cytokeratin 5 is a 58 kD protein, which is closely related to Cytokeratin 6. Cytokeratin 5 and6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina,squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from mostadenocarcinomas.
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Specificity
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This antibody reacts with Cytokeratin 5 intermediate filament protein. Cellular localization: Cytoplasmic. Species: Human. Others not tested.
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Application Notes
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Immunohistochemistry on Paraffin Embedded Sections: 1/50-1/75 (ABC method),Incubation of 30 minutes at room temperature. We suggest an Formalin fixed paraffin embedded tissue sections require high temperatureantigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended positive control: Skin. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
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Restrictions
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For Research Use only
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Alternatives for antigen "Cytokeratin 5 (KRT5)", type "Antibodies"
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Hosts
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Rabbit (15), Mouse (11), Guinea Pig (2)
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Reactivities
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Human (27), Mouse (Murine) (3), Rat (Rattus) (3), Cow (Bovine) (1)
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Applications
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23), Western Blotting (WB) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Enzyme Immunoassay (EIA) (4), ELISA (3), Immunohistochemistry (IHC) (3), Immunofluorescence (IF) (1)
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Epitopes
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C-Term (9)
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