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S-100 antibody
| Antigen | S-100 |
| Clonality | Monoclonal (4C4-9) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus) |
| Application |
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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4 references available |
| Catalog no. | ABIN115196 |
| Quantity | 0,5 ml (Variants) |
| Price | 195.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: S100 Calcium binding protein, S-100 protein, S100A, S100B, S-100 protein alpha chain,S-100 protein beta chain, Astrocyte Marker, S-100 protein alpha subunit, S-100 proteinbeta subunit, S100 Alpha, S100 Beta |
| Alternative name | S100 |
| Gene ID | 528735 |
| Swiss-Prot | P02639 |
| Immunogen | BALB/C mice were immunized with purified bovine brain S-100 protein. |
| Isotype | IgG2a (Matching secondary antibodies) |
| Clone | 4C4-9 |
| Description | S-100 belongs to the family of calcium binding proteins such as calmodulin and troponinC. S-100A and S-100B proteins are two members of the S-100 family. S-100A is composedof an alpha and beta chain whereas S-100B is composed of two beta chains. |
| Specificity | This antibody reacts with S-100 protein. It stains Schwannomas, ependymomas, astrogliomas, almost all benign and malignantmelanomas, and their metastases. Cellular Localization: Cytoplasmic. Species Reactivity: Tested: Human, Cow, Mouse and Rat. |
Application Details
| Application Notes | Immunohistochemistry on Paraffin Embedded Sections: Use at 1/50-1/100 dilution in anABC method for 30 minutes at room temperature (No treatment is required). Recommended Positive Control: Melanoma. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Research Area | Cell Cycle |
| Restrictions | For Research Use only |
Publications
| Publications |
Barrett, Scully: "S100 protein in oral biology and pathology." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 23, Issue 10, pp. 433-40, 1995 (PubMed).
Matsushima, Mori, Adachi et al.: "S100 protein positive human breast carcinomas: an immunohistochemical study." in: Journal of surgical oncology, Vol. 55, Issue 2, pp. 108-13, 1994 (PubMed). McLaren, Cossar: "The immunohistochemical localization of S100 in the diagnosis of papillary carcinoma of the thyroid." in: Human pathology, Vol. 27, Issue 7, pp. 633-6, 1996 (PubMed). Joshi, Lee, Pedersen et al.: "The role of immunocytochemical markers in the differential diagnosis of proliferative and neoplastic lesions of the breast." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 9, Issue 1, pp. 57-62, 1996 (PubMed). |
Alternatives
Alternatives for antigen "S-100", type "Antibodies"
| Hosts | Rabbit (20), Mouse (13), Goat (1) |
| Reactivities | Human (30), Cow (Bovine) (20), Mouse (Murine) (20), Rat (Rattus) (20), Monkey (11), Chicken (1), Kangaroo (1) |
| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (26), Immunohistochemistry (Frozen Sections) (IHC (fro)) (15), Immunohistochemistry (IHC) (8), Flow Cytometry (FACS) (6), Immunofluorescence (IF) (6), Western Blotting (WB) (5), ELISA (2), Enzyme Immunoassay (EIA) (1) |
| Conjugates | FITC (4) |
