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beta Amyloid antibody (Amyloid beta) (AA 1-40)

Details for Product anti-Abeta Antibody No. ABIN115238, Supplier: Log in to see
Antigen
  • aaa
  • abeta
  • abpp
  • ad1
  • appi
  • ctfgamma
  • cvap
  • pn2
  • APP
  • ABPP
Epitope
AA 1-40
80
47
21
13
9
4
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
203
23
11
6
3
3
2
2
1
1
1
1
Host
Mouse
157
55
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This beta Amyloid antibody is un-conjugated
16
8
5
5
5
5
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
142
123
49
43
32
29
26
20
10
8
5
5
3
2
2
2
2
1
1
1
Supplier
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Immunogen A synthetic beta-amyloid peptide (1-40) conjugated to KLH
Clone BAM-10
Isotype IgG1
Purification Ascites
Alternative Name Amyloid beta (Abeta Antibody Abstract)
Background The presence of a large number of neuritic plaques (senile) and neurofibrillary tangles in the cerebral cortex is used a pathological marker for a disease state and presents the major criterion for the diagnosis of Alzheimer's disease at autopsy.Synonyms: Amyloid beta peptide
Research Area Neurology, Alzheimer's Disease
Pathways
Application Notes Immunohistochemistry: dilute 1: 50-1: 100 in an ABC method (incubation time 30 minutes atroom temperature). Suitable for formalin/paraffin tissues and frozen tissues. We suggest an incubation period of 30 minutes at room temperature. Recommended positive control: Brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Abd-El-Aleem, Ferguson, Appleton et al.: "Expression of cyclooxygenase isoforms in normal human skin and chronic venous ulcers." in: The Journal of pathology, Vol. 195, Issue 5, pp. 616-23, 2001 (PubMed).

Yoshida, Fukumura, Fujita et al.: "The distribution of cyclooxygenase-1 in human temporomandibular joint samples: an immunohistochemical study." in: Journal of oral rehabilitation, Vol. 28, Issue 6, pp. 511-6, 2001 (PubMed).

Deininger, Meyermann, Trautmann et al.: "Cyclooxygenase (COX)-1 expressing macrophages/microglial cells and COX-2 expressing astrocytes accumulate during oligodendroglioma progression." in: Brain research, Vol. 885, Issue 1, pp. 111-6, 2001 (PubMed).