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Amyloid beta (Abeta) (AA 1-40) antibody

Antigen

Amyloid beta (Abeta)
Synonyms AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, CTFgamma, aaa, ad1, pn2, abpp, appi, cvap, abeta, MGC88882, ctfgamma, APP
Binding Site
Alternatives

AA 1-40
Clonality Monoclonal (BAM-10)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)
3 references available
Catalog no. ABIN115238
Quantity
Price 484.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name Amyloid beta
Immunogen A synthetic beta-amyloid peptide (1-40) conjugated to KLH
Cross-Reactivity Human
Isotype IgG1
Clone BAM-10
Description The presence of a large number of neuritic plaques (senile) and neurofibrillary tangles inthe cerebral cortex is used a pathological marker for a disease state and presents themajor criterion for the diagnosis of Alzheimer's disease at autopsy.
Specificity This antibody reacts with beta-amyloid protein. It stains Amyloid plaques within the cortex,and Amyloid deposits in blood vessels. Beta-amyloid deposits are also detected in Lewybody dementia, Down's syndrome, amyloidosis and in Gram-Parkinson dementia complex. Cellular localization: Cytoplasmic. Species: Human. Others not tested.

Application Details
Publications Alternatives Variants back to top

Application Notes Immunohistochemistry: dilute 1: 50-1: 100 in an ABC method (incubation time 30 minutes atroom temperature). Suitable for formalin/paraffin tissues and frozen tissues. We suggest an incubation period of 30 minutes at room temperature. Recommended positive control: Brain. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Purification Ascites
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Neurology, Alzheimer's Disease
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Deininger, Meyermann, Trautmann et al.: "Cyclooxygenase (COX)-1 expressing macrophages/microglial cells and COX-2 expressing astrocytes accumulate during oligodendroglioma progression." in: Brain research, Vol. 885, Issue 1, pp. 111-6, 2001 (PubMed).

Yoshida, Fukumura, Fujita et al.: "The distribution of cyclooxygenase-1 in human temporomandibular joint samples: an immunohistochemical study." in: Journal of oral rehabilitation, Vol. 28, Issue 6, pp. 511-6, 2001 (PubMed).

Abd-El-Aleem, Ferguson, Appleton et al.: "Expression of cyclooxygenase isoforms in normal human skin and chronic venous ulcers." in: The Journal of pathology, Vol. 195, Issue 5, pp. 616-23, 2001 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Amyloid beta (Abeta)", type "Antibodies"
Hosts Rabbit (94), Mouse (86), Chicken (3)
Reactivities Human (147), Mouse (Murine) (67), Rat (Rattus) (57), Chicken (39), Cow (Bovine) (39), Dog (Canine) (39), Pig (Porcine) (39), Guinea Pig (26), Horse (Equine) (26)
Applications Western Blotting (WB) (96), ELISA (85), Immunofluorescence (IF) (66), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (54), Immunohistochemistry (IHC) (34), Immunoprecipitation (IP) (20), Immunocytochemistry (ICC) (14), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (12), Immunoelectron Microscopy (IEM) (4), ELISA (Capture) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Dot Blot (Dot) (1), ELISA (Detection) (1), Fluorescence Microscopy (FM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Radioimmunoassay (RIA) (1)
Conjugates Biotin (10), FITC (7), Cy3 (4), Cy5 (4), Cy5.5 (4), Cy7 (4), Gold (4), HRP (4), PE (4), PE,Cy3 (4), PE,Cy5 (4), PE,Cy7 (4), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 647 (1)
Epitopes AA 1-28 (26), N-Term (18), AA 25-35 (15), AA 1-40 (13), AA 31-35 (13), AA 1-42 (9), AA 1-14 (6), AA 1-17 (5), C-Term (5), AA 1-16 (4), AA 1-8 (4), AA 1-40,AA 1-42 (3), AA 3-16 (3), AA 1-43 (2), AA 18-29 (2), AA 32-40 (2), C-Term, AA 1-40 (2), C-Term, AA 1-42 (2), AA 1-24 (1), AA 17-42 (1), AA 7-18 (1), AA 8-17 (1), C-Term , AA 1-43 (1), C-Term, AA 1-40, AA 1-42 (1), C-Term, AA 32-40 (1), C-Term,AA 1-40 (1), C-Term,AA 1-40,AA1-42 (1), C-Term,AA 1-42 (1), C-Term,AA 1-43 (1), Precurser (1)