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Details for Product No. ABIN115245

Linker For Activation of T Cells (LAT) (C-Term) antibody

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Antigen
Synonyms LAT1, pp36, LAT, lat
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN115245
Quantity 1 mL
Price
621.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Prokaryotic recombinant protein corresponding to a region of 120 amino acids with in the C- terminus of the LAT molecule.
Clone 3-8
Isotype IgG1
Specificity Reacts to Linker for Activation of T Cells (LAT) Cellular Localization: Membrane
Purification Supernatant
Alternative Name LAT
Background Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.
Alternate names: 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-Cells Family Member 1, p36-38, pp36
Gene ID 27040
NCBI Accession NP_001014987
UniProt O43561
Research Area Signaling, Adaptive Immunity
Application Notes Immunohistochemistry on paraffin sections: diluted of 1: 25 to 1: 50 in an ABC method (60 minutes at room temperature)Recommended Positive Control: TonsilOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 10mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Alternatives for antigen "Linker For Activation of T Cells (LAT)", type "Antibodies"
Hosts (108), (47), (7), (1)
Reactivities (155), (83), (81), (48), (36), (24), (1)
Applications (109), (62), (40), (33), (29), (21), (8), (7), (3), (3), (1), (1)
Conjugates (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (1)
Epitopes (16), (14), (13), (8), (7), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1)
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