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Linker For Activation of T Cells (LAT) antibody

Antigen

Linker For Activation of T Cells (LAT)
Synonyms LAT1, pp36, MGC108666, LAT, MGC157208, lat
Clonality Monoclonal (3-8)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN115246
Quantity
Price 363.00 $   Plus shipping costs $45.00
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Additional Information
Application Details Alternatives Variants back to top

Alternative name LAT
Gene ID 27040
UniProt O43561
Immunogen Prokaryotic recombinant protein corresponding to a region of 120 amino acids with in theC-terminus of the LAT molecule.
Cross-Reactivity Human
Isotype IgG1
Clone 3-8
Description Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), whichplays an important role in linking engagement of the TCR to the biochemical events of T cellactivation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cellareas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces,platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells,monocytes, epithelial histiocytes and dendritic cells.
Characteristics Synonyms: pp36, p36-38, 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-CellsFamily Member 1

Application Details
Alternatives Variants back to top

Application Notes Immunohistochemistry on paraffin sections: diluted of 1: 25 to 1: 50 in an ABC method (60 minutes at room temperature)Recommended Positive Control: TonsilOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Purification Supernatant
Buffer 10mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Signaling, Adaptive Immunity
Restrictions For Research Use only

Alternatives
Application Details Variants back to top

Alternatives for antigen "Linker For Activation of T Cells (LAT)", type "Antibodies"
Hosts Rabbit (90), Mouse (34), Goat (4), Sheep (1)
Reactivities Human (122), Rat (Rattus) (72), Mouse (Murine) (71), Chicken (19), Cow (Bovine) (19), Dog (Canine) (19), Rabbit (18), Cat (Feline) (1), Chimpanzee (1), Monkey (1)
Applications Western Blotting (WB) (71), Immunofluorescence (IF) (47), ELISA (34), Immunoprecipitation (IP) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (19), Flow Cytometry (FACS) (17), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (9), Immunohistochemistry (IHC) (8), Immunocytochemistry (ICC) (7), Immunoelectron Microscopy (IEM) (3), Dot Blot (DB) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 488 (5), PE (5), Alexa Fluor 350 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), Biotin (3), Cy3 (3), Cy5 (3), Cy5.5 (3), Cy7 (3), FITC (3), Gold (3), HRP (3), PE-Cy3 (3), PE-Cy5 (3), PE-Cy5.5 (3), PE-Cy7 (3), Un-conjugated (3), APC (2), Alexa Fluor 700 (2), Dyomics 647 (2)
Epitopes C-Term (24), pTyr200 (20), pTyr161 (19), Cytoplasmic Domain (10), pTyr191 (4), AA 31-233 (3), pTyr171 (2), AA 30-113 (1), AA 70-120 (1), Internal Region (1), N-Term (1), pTyr132 (1), pTyr226 (1)