PPY antibody

Catalog No. ABIN115336

Product Details anti-PPY Antibody

Target: PPY (Pancreatic Polypeptide (PPY))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPY antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody reacts with Pancreatic Polypeptide. It stains the periphery of islets, exocrine pancreatic parenchyma, and the epithelium of small and medium sized ducts and acinar cells.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogen: Synthetic Human Pancreatic Polypeptide conjugated to Keyhole Limpet Hemocyanin.

Application Details

Application Notes: Immunohistochemistry on Frozen and Paraffin Embedded Sections: diluted of 1/25-1/50 inan ABC method (30 minutes at room temperature)Recommended Positive Control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one mounth or (in aliquots) at -20 °C for longer.

Target Details for PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Alternative Name: Pancreatic Prohormone (PPY Products)

Synonyms: PPY antibody, PNP antibody, PP antibody, AV061413 antibody, IGSPP antibody, pancreatic polypeptide antibody, peptide YY antibody, PPY antibody, Ppy antibody, PYY antibody

Background: Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.Synonyms: Obinepitide, PNP, PPY, Pancreatic polypeptide

Gene ID: 5539

NCBI Accession: NP_002713

UniProt: P01298

Pathways: Feeding Behaviour