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Gastrin antibody

GAST Reactivity: Human IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115354
  • Target See all Gastrin (GAST) Antibodies
    Gastrin (GAST)
    Reactivity
    • 53
    • 32
    • 28
    • 6
    • 2
    • 1
    Human
    Host
    • 55
    • 11
    • 1
    Rabbit
    Clonality
    • 56
    • 11
    Polyclonal
    Conjugate
    • 38
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Gastrin antibody is un-conjugated
    Application
    • 54
    • 30
    • 25
    • 14
    • 13
    • 13
    • 12
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    The antibody is specific against gastrin-containing cells. This antibody reacts with human gastrin I and human gastrin I fragments.
    Cellular Localization: Cytoplasmic
    Purification
    Purified
    Immunogen
    Recombinant Gastrin conjugated to KLH.
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    Discover our top product GAST Primary Antibody
  • Application Notes
    Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Stomach
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    containing sodium azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Gastrin (GAST)
    Alternative Name
    Gastrin (GAST Products)
    Synonyms
    GAS antibody, Gas antibody, PPG34 antibody, GAST antibody, gastrin antibody, GAST antibody, Gast antibody
    Background
    Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.Synonyms: GAS, GAST
    Gene ID
    2520
    NCBI Accession
    NP_000796
    UniProt
    P01350
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