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Details for Product No. ABIN115356

Adrencocorticotropic hormone (ACTH) antibody

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Antigen
Reactivity
»Alternatives Human, Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Pubmed 4 references available
Catalog no. ABIN115356
Quantity 1 mL
Price
456.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic Human ACTH 1-24.
Specificity This antibody reacts with Human ACTH in a wide variety of Mammalian species. Traces of contaminating antibodies have been removed by solid phase absorption. Cellular Localization: Cytoplasmic.
Purification Serum
Alternative Name Adrenocorticotropic Hormone (ACTH)
Background ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.
Alternate names: Adrenocorticotropic hormone, Corticotropin, POMC
Gene ID 5443
NCBI Accession NP_000930.1
UniProt P01189
Research Area Hormones
Application Notes Immunohistochemistry on Formalin Fixed, Paraffin Embedded Tissue Sections: Use at1/50-1/250 dilution in an ABC method (30 minutes at RT). Recommended Positive Control: PituitaryOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Liu, Zou, Slaughter et al.: "DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis." in: Cell, Vol. 89, Issue 2, pp. 175-84, 1997 (PubMed).

Enari, Sakahira, Yokoyama et al.: "A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD." in: Nature, Vol. 391, Issue 6662, pp. 43-50, 1998 (PubMed).

Sakahira, Enari, Nagata: "Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis." in: Nature, Vol. 391, Issue 6662, pp. 96-9, 1998 (PubMed).

McCarty, Toh, Li: "Study of DFF45 in its role of chaperone and inhibitor: two independent inhibitory domains of DFF40 nuclease activity." in: Biochemical and biophysical research communications, Vol. 264, Issue 1, pp. 176-80, 1999 (PubMed).

Alternatives for antigen "Adrencocorticotropic hormone (ACTH)", type "Antibodies"
Hosts (118), (52), (2), (1)
Reactivities (158), (52), (39), (25), (24), (17), (12), (12), (2), (2), (1)
Applications (76), (68), (40), (27), (18), (15), (11), (11), (5), (4), (2), (2), (2), (2)
Conjugates (7), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (56), (26), (14), (12), (6), (3), (3), (1)
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