You are viewing an incomplete version of our website. Please click to reload the website as full version.

PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (N-Term)

Details for Product anti-PARP1 Antibody No. ABIN115385, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, LD21673.3prime, PARP, PARP-1, PARP1, dPARP, parp, ADPRT, ADPRT 1, ADPRT1, ARTD1, PPOL, pADPRT-1, Adprt, Parp-1, adprt ... show more
BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, LD21673.3prime, PARP, PARP-1, PARP1, dPARP, parp, ADPRT, ADPRT 1, ADPRT1, ARTD1, PPOL, pADPRT-1, Adprt, Parp-1, adprt1, padprt-1, ppol, 5830444G22Rik, AI893648, Adprp, Adprt1, C80510, parp-1, sPARP-1 show less
Alternatives
Show less
Epitope
N-Term
(69), (20), (20), (20), (20), (20), (20), (19), (19), (19), (17), (16), (16), (14), (14), (13), (12), (10), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(393), (61), (59), (12), (5), (4), (4), (3), (3), (1), (1), (1), (1), (1)
Host
Rabbit
(394), (47), (1)
Clonality
Polyclonal
Conjugate
This PARP1 antibody is un-conjugated
(25), (25), (24), (24), (23), (23), (2), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(229), (226), (172), (50), (45), (42), (37), (28), (16), (13), (10), (6), (4), (3), (3), (2), (1), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.5 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen A synthetic peptide from the N-terminal region of human PARP.
Specificity This antibody reacts with a 116 kDa protein, known as PARP.
Cellular Localization: Nuclear.
Purification Purified
Alternative Name PARP1 (PARP1 Antibody Abstract)
Background Proteolysis of PARP to its stable 85 kD fragment is an early marker of apoptosis and is mediated by Caspase (CPP32) protein. PARP uses nicotinamide adenine dinucleotide (oxidized form) as a substrate to catalyze the transfer of ADP-ribose to a variety of nuclear acceptors.Synonyms: ADPRT, ADPRT 1, NAD(+) ADP-ribosyltransferase 1, PARP-1, PPOL, Poly [ADP-ribose] polymerase 1, Poly[ADP-ribose] synthetase 1
Gene ID 142
NCBI Accession NP_001609
UniProt P09874
Pathways Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair
Application Notes Western Blot. Immunohistochemistry on Paraffin Embedded Sections: Use at 1/25-1/50 dilution in anABC method for 30 minutes at room temperature. High temperature treatment offormalin-fixed tissue sections with 10 mM citrate buffer, pH 6.0 must be performed prior tothe immunostaining. Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Background publications Tewari, Quan, ORourke et al.: "Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase." in: Cell, Vol. 81, Issue 5, pp. 801-9, 1995 (PubMed).

Lamarre, Talbot, de Murcia et al.: "Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study." in: Biochimica et biophysica acta, Vol. 950, Issue 2, pp. 147-60, 1988 (PubMed).

Catalog No. ABIN115385
$478.50
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)