X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (N-Term) antibody

Details for Product No. ABIN115395, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms MGC69118, im:7142103, zgc:101608, si:dkey-11b8.1, xrcc3, XRCC3, CMM6, 4432412E01Rik, AI182522, AW537713
Alternatives
Epitope
N-Term
(8), (7), (7), (5), (5), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(107), (11), (1), (1)
Host
Rabbit
(80), (27), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(92), (30), (28), (17), (7), (4), (3), (1), (1), (1), (1), (1)
Pubmed 2 references available
ProductDetails: Supplier Login to see New
ProductDetails: Supplier Product Number Login to see New
Quantity 0.5 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen A synthetic peptide derived from the N-terminus of human XRCC3 protein.
Specificity This antibody reacts with a 32 kDa protein, known as XRCC3 (X-Ray Cross Complementing 3).
Cellular Localization: Nuclear, cytoplasmic
Purification Purified
Alternative Name XRCC3 (XRCC3 Antibody Abstract)
Background XRCC3 is essential for repairing the double strand DNA breaks by homologous recombination between sister chromatids. It is homologous to Rad1. Five human homologues of RAD 51, XRCC2, XRCC3, RAD51B, RAD51C, RAD51D, interact among themselves to form one big complex or several smaller complexes.Synonyms: DNA repair protein XRCC3, X-ray repair cross-complementing protein 3
Gene ID 7517
NCBI Accession NP_001093588
UniProt O43542
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Pathways DNA Damage Repair
Application Notes Western Blot: 1: 100-500. Immunohistochemistry on paraffin embedded sections: diluted of 1: 25-1: 50 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Testis
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (N-Term) antibody (ABIN115395) Western blot analysis of human lung cell extract with XRCC3 antibody. ABIN115394
Background publications Johnson, Liu, Jasin: "Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination." in: Nature, Vol. 401, Issue 6751, pp. 397-9, 1999 (PubMed).

Tambini, George, Rommens et al.: "The XRCC2 DNA repair gene: identification of a positional candidate." in: Genomics, Vol. 41, Issue 1, pp. 84-92, 1997 (PubMed).

Catalog No. ABIN115395
$478.50
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?