PTGS2 antibody (C-Term)

Catalog No. ABIN115419

Product Details anti-PTGS2 Antibody

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGS2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts with a 70 kDa protein.
Cellular Localization: Cytoplasmic, membrane

Purification: Purified

Immunogen: Recombinant protein corresponding to c-terminus of rat COX2.

Application Details

Application Notes: Immunohistochemistry on paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Lung and colon carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM citrate buffer, pH 6.0 containing sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PTGS2

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Alternative Name: Cyclooxygenase 2 (PTGS2 Products)

Synonyms: COX-2 antibody, COX2 antibody, GRIPGHS antibody, PGG/HS antibody, PGHS-2 antibody, PHS-2 antibody, hCox-2 antibody, Cox-2 antibody, Pghs2 antibody, TIS10 antibody, Cox2 antibody, cox-2 antibody, CEF147 antibody, PGHS2 antibody, PHSII antibody, cox2 antibody, gripghs antibody, pgg/hs antibody, pghs-2 antibody, phs-2 antibody, PTGS2 antibody, hcox-2 antibody, fj02a10 antibody, ptgs2 antibody, unp1239 antibody, wu:fj02a10 antibody, zCOX-2 antibody, si:dkey-97o5.6 antibody, prostaglandin-endoperoxide synthase 2 antibody, prostaglandin G/H synthase 2 antibody, prostaglandin-endoperoxide synthase 2S homeolog antibody, prostaglandin-endoperoxide synthase 2a antibody, prostaglandin-endoperoxide synthase 2b antibody, PTGS2 antibody, Ptgs2 antibody, LOC100136456 antibody, ptgs2.S antibody, ptgs2 antibody, ptgs2a antibody, ptgs2b antibody

Background: COX2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters and cytokines that induce its expression. COX2 expression markedly increased in 85-90 % of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.Synonyms: COX2, Cyclooxygenase-2, PGH synthase 2, PGHS-2, PGHS2, PHS II, PTGS2, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2

Gene ID: 19225

NCBI Accession: NP_035328

UniProt: Q05769

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation