Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ADIPOQ antibody (N-Term)

ADIPOQ Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115498
  • Target See all ADIPOQ Antibodies
    ADIPOQ (Adiponectin (ADIPOQ))
    Binding Specificity
    • 18
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 140
    • 58
    • 36
    • 17
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 125
    • 66
    • 6
    • 3
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 133
    • 69
    Polyclonal
    Conjugate
    • 121
    • 31
    • 15
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADIPOQ antibody is un-conjugated
    Application
    • 122
    • 101
    • 67
    • 35
    • 29
    • 27
    • 26
    • 21
    • 20
    • 12
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MRGSHHHHHH GSGHDQETTT QGPGVLLPLP KGACTGWMAG IPGHPGHNGA PGRDGRDGTP GEKGEKGDPG LIGPKGDIGE TGVPGAEGPR GFPGIQGRKG EPGEGAYVYR SAFSVGLETY VTIPNMPIRF TKIFYNQQNH YDGSTGKFHC NIPGLYYFAY HITVYMKDVK VSLFKKDKAM LFTYDQYQEN NVDQASGSVL LHLEVGDQVW LQVYGEGERN GLYADNDNDS TFTGFLLYHD TN Remarks: Source of Antigen: E.Coli
    Specificity
    The antibody was raised in rabbits by immunization with the recombinant Adiponectin.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography.
    Immunogen
    The immunization antigen (26.4 kDa) is a protein containing 242 AA of recombinant Human Adiponectin. N-Terminal His-tag, 12 extra AA (highlighted).
    Top Product
    Discover our top product ADIPOQ Primary Antibody
  • Application Notes
    Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 0.1 mL of deionized water and let and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
    Buffer
    0.05 M phosphate buffer, 0.5 M NaCl, pH 7.2, None
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    Expiry Date
    6 months
  • Badakhshi, Marnitz, Scherer, Budach, Haisch: "[Adenoid cystic carcinoma of the oropharynx. Brachytherapy for the treatment of local recurrences]" in: HNO, Vol. 56, Issue 3, pp. 328-31, (2008) (PubMed).

  • Target
    ADIPOQ (Adiponectin (ADIPOQ))
    Alternative Name
    Adiponectin (ADIPOQ Products)
    Synonyms
    ADP antibody, DCAF9 antibody, 6720489L24Rik antibody, 9330209L04Rik antibody, Adp antibody, Mamdc1 antibody, RNSVSP4U antibody, SVSIV1 antibody, Svp4 antibody, ACDC antibody, ACRP30 antibody, ADIPQTL1 antibody, ADPN antibody, APM-1 antibody, APM1 antibody, GBP28 antibody, apM-1 antibody, 30kDa antibody, APN antibody, Acdc antibody, Acrp30 antibody, Ad antibody, adipo antibody, apM1 antibody, ADN antibody, acrpl antibody, adipo-b antibody, adipoql antibody, zgc:153584 antibody, adipoq antibody, WD and tetratricopeptide repeats 1 antibody, MAM domain containing glycosylphosphatidylinositol anchor 2 antibody, seminal vesicle secretory protein 4 antibody, adiponectin, C1Q and collagen domain containing antibody, adiponectin, C1Q and collagen domain containing, b antibody, adiponectin, C1Q and collagen domain containing L homeolog antibody, WDTC1 antibody, Mdga2 antibody, Svs4 antibody, ADIPOQ antibody, Adipoq antibody, adipoqb antibody, adipoq.L antibody
    Background
    Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 aminoacid protein, the product of the apM1 gene, which is physiologically active and specifically and highly expressed in adipose cells. The protein belongs to the soluble defence collagen superfamily, it has a collagen-like domain structurally homologous with collagen VIII and X and complement factor C1q-like globular domain. Adiponectin forms homotrimers, which are the building blocks for higher order complexes found circulating in serum. Together, these complexes make up approximately 0.01 % of total serum protein. Adiponectin receptors AdipoR1 and AdipoR2 have been recently cloned, AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. Paradoxically, adipose tissue-expressed adiponectin levels are inversely related to the degree of adiposity. Adiponectin concentrations correlate negatively with glucose, insulin, triglyceride concentrations, liver fat content and body mass index and positively with high-density lipoproteincholesterol levels, hepatic insulin sensitivity and insulin-stimulated glucose disposal. Adiponectin has been shown to increase insulin sensitivity and decrease plasma glucose by increasing tissue fat oxidation. Of particular interest is that low adiponectin serum levels predict type 2 diabetes independent of other risk factors. Adiponectin also inhibits the inflammatory processes of atherosclerosis suppressing the expression of adhesion and cytokine molecules in vascular endothelial cells and macrophages, respectively. This adipokine plays a role as a scaffold of newly formed collagen in myocardial remodelling after ischaemic injury and also stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signalling in endothelial cells. Low serum adiponectin levels are found in patients with coronary artery disease. Moreover, high circulating levels of adiponectin are associated with decreased risk of myocardial infarction, independent of other factors. Altogether, adiponectin has the potential to become a clinically relevant parameter to be measured routinely in subjects at risk for type 2 diabetes, atherosclerosis and the metabolic syndrome.Synonyms: 30 kDa adipocyte complement-related protein, ACDC, ACRP30, ADIPOQ, APM1, Adipocyte, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, C1q and collagen domain-containing protein, GBP28, Gelatin-binding protein
    Gene ID
    9370
    NCBI Accession
    NP_001171271
    UniProt
    Q15848
You are here:
Support