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Periostin antibody

POSTN Reactivity: Human, Mouse, Rat, Chicken WB, IHC (p), EIA, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115513
  • Target See all Periostin (POSTN) Antibodies
    Periostin (POSTN)
    Reactivity
    • 79
    • 38
    • 25
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Chicken
    Host
    • 78
    • 16
    • 3
    • 2
    • 2
    Rabbit
    Clonality
    • 72
    • 29
    Polyclonal
    Conjugate
    • 54
    • 17
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Periostin antibody is un-conjugated
    Application
    • 73
    • 46
    • 36
    • 14
    • 14
    • 11
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Sequence
    MGHHHHHHHH HHSSGHIEGR HMRNNHYDKI LAHSRIRGRD QGPNVCALQQ ILGTKKKYFS TCKNWYKKSI CGQKTTVLYE CCPGYMRMEG MKGCPAVLPI DHVYGTLGIV GATTTQRYSD ASKLREEIEG KGSFTYFAPS NEAWDNLDSD IRRGLESNVN VELLNALHSH MINKRMLTKD LKNGMIIPSM YNNLGLFINH YPNGVVTVNC ARIIHGNQIA TNGVVHVIDR VLTQIGTSIQ DFIEAEDDLS SFRAAAITSD ILEALGRDGH FTLFAPTNEA FEKLPRGVLE RFMGDKVASE ALMKYHILNT LQCSESIMGG AVFETLEGNT IEIGCDGDSI TVNGIKMVNK KDIVTNNGVI HLIDQVLIPD SAKQVIELAG KQQTTFTDLV AQLGLASALR PDGEYTLLAP VNNAFSDDTL SMVQRLLKLI LQNHILKVKV GLNELYNGQI LETIGGKQLR VFVYRTAVCI ENSCMEKGSK QGRNGAIHIF REIIKPAEKS LHEKLKQDKR FSTFLSLLEA ADLKELLTQP GDWTLFVPTN DAFKGMTSEE KEILIRDKNA LQNIILYHLT PGVFIGKGFE PGVTNILKTT QGSKIFLKEV NDTLLVNELK SKESDIMTTN GVIHVVDKLL YPADTPVGND QLLEILNKLI KYIQIKFVRG STFKEIPVTV Y Remarks: The immunizati on antigen (75 kDa) is a protein containing 648 amino acids of recombinan t Human OSF-2 and 23 amino acids, N-Terminal HisTag and Xa - cleavage site (highlighte d). The antigen contains amino acid residues 22 to 669 of the Human OSF-2 precursor. The antigen includes all four fasciclin domains of OSF-2.
    Specificity
    The antibody recognizes OSF-2.
    Purification
    Immunoaffinity Chromatography on Immoblized Recombinant Human OSF2
    Immunogen
    Recombinant Human OSF-2 Source of Antigen: E. coli.
    Top Product
    Discover our top product POSTN Primary Antibody
  • Application Notes
    ELISA. Western blot (0.1-1 μg/mL). Immunohistochemistry on Paraffin (1/100-1/5,000) and Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Add 0.05 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
    Buffer
    0.05 M Phosphate Buffer, 0.1 M NaCl, pH 7.2 without preservatives
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Stable the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Periostin (POSTN)
    Alternative Name
    Periostin (POSTN Products)
    Synonyms
    fa99h07 antibody, pn antibody, postn antibody, wu:fa99h07 antibody, wu:fc70f09 antibody, zgc:153873 antibody, LOC100008945 antibody, osf-2 antibody, pdlpostn antibody, periostin antibody, OSF-2 antibody, OSF2 antibody, PDLPOSTN antibody, PN antibody, RP11-412K4.1 antibody, A630052E07Rik antibody, AI747096 antibody, Osf2 antibody, PLF antibody, peri antibody, Plf antibody, periostin antibody, periostin, osteoblast specific factor b antibody, periostin, osteoblast specific factor antibody, POSTN antibody, postnb antibody, postn antibody, Postn antibody
    Background
    Periostin is a disulfide linked 90 kDa 811 amno acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta-1(TGFbeta1) and bone morphogenetic protein (BMP)-2. OSF-2 has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF-2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart.Synonyms: OSF-2, OSF2, Osteoblast-specific factor 2, PN, POSTN
    Gene ID
    10631
    NCBI Accession
    NP_001129406
    UniProt
    Q15063
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