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VEGFA antibody (N-Term)

VEGFA Reactivity: Human, Rat, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115674
  • Target See all VEGFA Antibodies
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    Binding Specificity
    • 19
    • 15
    • 15
    • 15
    • 15
    • 15
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 155
    • 125
    • 97
    • 24
    • 20
    • 19
    • 19
    • 16
    • 12
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 203
    • 54
    • 13
    • 1
    Rabbit
    Clonality
    • 214
    • 56
    • 1
    Polyclonal
    Conjugate
    • 122
    • 41
    • 25
    • 12
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VEGFA antibody is un-conjugated
    Application
    • 206
    • 93
    • 65
    • 65
    • 52
    • 32
    • 27
    • 22
    • 22
    • 15
    • 15
    • 12
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    The antibody will react with all VEGF-A isoforms.
    Purification
    Affinity Chromatography with immobilized Protein A
    Immunogen
    Highly purified N-terminal 20 amino acid peptide of Human VEGF-A
    Top Product
    Discover our top product VEGFA Primary Antibody
  • Application Notes
    ELISA: To detect Human VEGF by Direct ELISA a concentration of at least 0.5-2 μg/mL isrequired. This purified IgG, in combination with compatible secondary reagents, allows thedetection of 1,0- 2,5 ng/well of recombinant Human VEGF165 or other VEGF splice forms. Western Blot: 5-10 μg/mL. It will detect 25 ng/lane of recombinant human and murineVEGF-A under reducing conditions, dimers are detected at higher protein concentrations.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in sterile water to a concentration of > 0.5 mg/mL
    Buffer
    PBS, pH 7.4 containing no preservative
    Preservative
    Without preservative
    Storage
    4 °C/-20 °C
    Storage Comment
    The lyophilized IgG is stable at 2-8 °C for at least one month and for longer when kept at -20 °C. When reconstituted the antibody is stable for at least six weeks at 2-4 °C.
  • Target
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    Alternative Name
    VEGF-A (VEGFA Products)
    Synonyms
    MVCD1 antibody, VEGF antibody, VPF antibody, Vegf antibody, Vegf120 antibody, Vegf164 antibody, Vegf188 antibody, Vpf antibody, vegf antibody, vegfa antibody, wu:fj82c06 antibody, VEGF-A antibody, VEGF164 antibody, eVEGF120 antibody, eVEGF164 antibody, vegf-a antibody, vpf antibody, vefg antibody, si:dkey-14d8.3 antibody, wu:fd42e02 antibody, vascular endothelial growth factor A antibody, vascular endothelial growth factor Aa antibody, vascular endothelial growth factor A L homeolog antibody, vascular endothelial growth factor Ab antibody, VEGFA antibody, Vegfa antibody, vegfaa antibody, vegfa.L antibody, vegfa antibody, vegfab antibody
    Background
    VEGF (vascular endothelial growth factor) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF189 and VEGF206) remain cell associated.Synonyms: VEGF, VEGFA, VPF, Vascular endothelial growth factor A, Vascular permeability factor
    Gene ID
    7422
    NCBI Accession
    NP_001020537
    UniProt
    P15692
    Pathways
    RTK Signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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