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Calcitonin-Related Polypeptide alpha (CALCA) antibody

Antigen

Calcitonin-Related Polypeptide alpha (CALCA)

Synonyms CALCA, CALC3, MGC152154, CT, KC, CGRP, CALC1, CGRP1, CGRP-I, MGC126648, CFP1, CGBP, SPP1, PCCX1, PHF18, hCGBP, HsT2645, 2410002I16Rik, 5830420C16Rik, CALC, calcitonin, calca, ci-ct
Clonality Monoclonal (SP17)
Host
Alternatives

Rabbit

Reactivity
Alternatives

Mammalian

Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN115714
Quantity 0.5 ml
Price 310.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Characteristics Synonyms: CALCA, CALC1
Alternative name Calcitonin
Swiss-Prot P01258
Immunogen Synthetic human calcitonin 1-32 amino acid peptide.
Format Supernatant
Isotype IgG  (Matching secondary antibodies)
Clone SP17
Description Staining for calcitonin may be used for the identification of a spectrum of C cellproliferative abnormalities ranging from C cell hyperplasia to invasive tumors.
Specificity This antibody recognizes Calcitonin, which is a 32 amino acid peptide, which can bedemonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granularpattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varyingdegrees of calcitonin activity. Species: Human, Monkey, Mouse, Rat, Dog, Horse, Sheep, Pig. Others not tested.

Application Details

Application Notes Immunohistochemistry on formalin-fixed paraffin embedded sections: dilute 1: 100 in anABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissuesections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0prior to immunostaining. Recommended Positive Control: Thyroid or Medullary carcinomaOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Cancer, Growth Factors, Hormones, Cytoskeleton, Microfilaments, Innate Immunity, Chemokines
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Calcitonin-Related Polypeptide alpha (CALCA)", type "Antibodies"
Hosts Rabbit (88), Mouse (12), Goat (7), Sheep (4), Chicken (2), Guinea Pig (2)
Reactivities Human (102), Rat (Rattus) (36), Dog (Canine) (27), Mouse (Murine) (20), Pig (Porcine) (10), Sheep (Ovine) (10), Monkey (7), Rabbit (7), Hamster (6), Cow (Bovine) (3), Horse (Equine) (2), Mammalian (2), Chicken (1), Guinea Pig (1), Reptile (1), Zebrafish (Danio rerio) (1)
Applications Immunofluorescence (IF) (47), Flow Cytometry (FACS) (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (33), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Radioimmunoassay (RIA) (20), Enzyme Immunoassay (EIA) (17), Western Blotting (WB) (17), ELISA (10), Immunohistochemistry (IHC) (9), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunoprecipitation (IP) (4), ELISA (Capture) (2), Immunoelectron Microscopy (IEM) (2), ELISA (Detection) (1)
Conjugates Biotin (6), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitopes AA 1-32 (6), C-Term (2)