CRNN
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
In PBS containing 1 % BSA and 0.01 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Contzler, Favre, Huber, Hohl: "Cornulin, a new member of the "fused gene" family, is expressed during epidermal differentiation." in: The Journal of investigative dermatology, Vol. 124, Issue 5, pp. 990-7, (2005) (PubMed).
Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines. It attenuates deoxycholic acid (DCA)-induced apoptotic cell death and the release of calcium. In overexpressed oral squamous carcinoma cell lines, cornulin negatively regulates cell proliferation by the induction of G1 arrest.