CUL9 antibody (C-Term)

Catalog No. ABIN117956

Product Details anti-CUL9 Antibody

Target: CUL9 (Cullin 9 (CUL9))

Binding Specificity: AA 2503-2517, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUL9 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Sequence: Human PARC (2517 aa 281.2 kDa): 1 mvgerhagdl mvplgprlqa ypeelirqrp ghdghpeyli rwsvlkcgev gkvgveegka 61 ehilmwlsap evyancpgll geralskglq hepagvsgsf prdpggldev amgemeadvq 121 alvrraarql aesgtpslta avlhtihvls ayasigpltg vfretgaldl lmhmlcnpep 181 qirrsagkml qalaahdags rahvllslsq qdgieqhmdf dsrytllelf aettsseehc 241 mafegihlpq ipgkllfslv krylcvtsll dqlnsspelg agdqsspcat reksrgqrel 301 efsmavgnli selvrsmgwa rnlseqgmsp prptrsifqp yisgpslllp tivttprrqg 361 wvfrqrsefs srsgygeyvq qtlqpgmrvr mlddyeeisa gdegefrqsn ngippvqvfw 421 qstgrtywvh whmleilgpe eatedkasaa vekgagatvl gtafpswdwn pmdglyplpy 481 lqpepqkner vgyltqaeww ellffikkld lceqqpifqn lwknldetlg ekalgeisvs 541 vemaesllqv lssrfegstl ndllnsqiyt kygllsneps ssstsrnhsc tpdpeeesks 601 easfseeete slkakaeapk teaeptktrt etpmaqsdsq lfnqllvteg mtlptemkea 661 askmaralrg pgprssldqh vaavvatvqi ssldtnlqls glsalsqave evterdhplv --- 1681 eaekelfied pspaisilvl sprcwpvspl cylyhprkcl ptefcdaldr fssfysqsqn 1741 hpvldmgphr rlqwtwlgra elqfgkqilh vstvqmwlll kfnqteevsv etllkdsdls 1801 pelllqalvp ltsgngpltl hegqdfphgg vlrlhepgpq rsgealwlip pqaylnvekd 1861 egrtleqkrn llscllvril kahgekglhi dqlvclvlea wqkgpnppgt lghtvaggva 1921 ctstdvlsci lhllgqgyvk rrddrpqilm yaapepmgpc rgqadvpfcg sqsetskpsp 1981 eavatlaslq lpagrtmspq eveglmkqtv rqvqetlnle pdvaqhllah shwgaeqllq 2041 sysedpepll laaglcvhqa qavpvrpdhc pvcvsplgcd ddlpslccmh ycckscwney 2101 lttrieqnlv lnctcpiadc paqptgafir aivsspevis kyekallrgy vescsnltwc 2161 tnpqgcdril crqglgcgtt cskcgwascf ncsfpeahyp ascghmsqwv ddggyydgms 2221 veaqskhlak liskrcpscq apieknegcl hmtcakcnhg fcwrclkswk pnhkdyyncs 2281 amvskaarqe krfqdynerc tfhhqarefa vnlrnrvsai hevppprsft flndacqgle 2341 qarkvlayac vysfysqdae ymdvveqqte nlelhtnalq illeetllrc rdlasslrll 2401 radclstgme llrriqerll ailqhsaqdf rvglqspsve aweakgpnmp gsqpqassgp 2461 eaeeeeedde ddvpewqqde fdeeldndsf sydesenldq etfffgdeee dedeayd

Specificity: This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human and mouse PARC. Cross reactivity with PARC from other sources is not known.

Purification: Delipidation and defibrination.

Immunogen: Prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 2503-2517 of Human PARC (C-terminus) coupled to KLH.

Application Details

Application Notes: This antibody reacts with human and mouse PARC by Western blot (1: 500-1: 1,000) andImmunoprecipitation. The antibody immunoprecipitates protein from cell lysates (usingHeLa, NIH-3T3, and others). To date co-immuno-precipitation using 35SIP has beennegative. A 281.2 kDa band corresponding to human PARC is detected. Most cell linesexpressing PARC can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 85 mg/mL (by Refractometry)

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C.

Target Details for CUL9

Target: CUL9 (Cullin 9 (CUL9))

Alternative Name: Cullin-9 (CUL9 Products)

Synonyms: H7AP1 antibody, PARC antibody, RP3-330M21.2 antibody, parc antibody, 1810035I07Rik antibody, Cul-9 antibody, Parc antibody, mKIAA0708 antibody, RGD1562008 antibody, cullin-9 antibody, cullin 9 antibody, cullin-9 antibody, CUL9 antibody, LOC100083225 antibody, cul9 antibody, LOC100561099 antibody, Cul9 antibody

Background: Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. PARC is a cullin family member that functions as a cytoplasmic anchor protein in p53-associated protein complexes. PARC regulates the subcellular localization of p53 and subsequent function. PARC forms a complex with p53 in the cytoplasm of unstressed cells and interacts with UBCH7 and UBCH8. PARC shows a cytoplasmic localization and is ubiquitously expressed in all tissues with highest expression in testis brain and kidney.Synonyms: CUL-9, H7AP1, KIAA0708, PARC, UbcH7-associated protein 1, p53-associated parkin-like cytoplasmic protein

Gene ID: 23113

NCBI Accession: NP_055904

UniProt: Q8IWT3