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CD11b antibody (FITC)

ITGAM Reactivity: Human, Mouse, Rabbit FACS Host: Rat Monoclonal M1-70-15 FITC
Catalog No. ABIN118142
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 259
    • 168
    • 62
    • 33
    • 17
    • 17
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    • 11
    • 7
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    • 1
    Human, Mouse, Rabbit
    Host
    • 137
    • 105
    • 103
    • 4
    • 1
    • 1
    Rat
    Clonality
    • 251
    • 96
    • 1
    Monoclonal
    Conjugate
    • 120
    • 37
    • 29
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    • 3
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    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is conjugated to FITC
    Application
    • 260
    • 84
    • 76
    • 72
    • 59
    • 40
    • 36
    • 27
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    • 20
    • 13
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    Flow Cytometry (FACS)
    Purification
    Affinity chromatography on Protein A
    Immunogen
    T cell enriched splenocytes from B10 mice. Spleen cells from immunised DA rats were fused with cells of the mouse NS1/1.Ag4.1 myeloma cell line.
    Clone
    M1-70-15
    Isotype
    IgG2b
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    Flow cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    MAC-1 is a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
    Gene ID
    10090
    UniProt
    P05555
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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