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T Cell Receptor (TCR) Vb 7 (AA 3-63) antibody

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Antigen
Epitope
AA 3-63
Reactivity
Mouse (Murine)
(1)
Host
Rat
(1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1)
Application
Flow Cytometry (FACS)
(1)
Pubmed 2 references available
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Quantity 0.2 mg
Shipping to United States ( )
Availability
Immunogen T-cell lymphoma TK1. Spleen cells from immunised mice were fused with cells of the P3-X63 Ag8.3 rat myeloma cell line
Clone TR310
Isotype IgG2b
Specificity This antibody reacts with the TCR Vb7 bearing T cells. Note that TCR Vb7 may not be present in mouse strains expressing MIS-1a haplotype.
Purification Purified
Research Area Immunology, Receptors, Signaling
Application Notes Flow cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 4-8°C for one month or at -20°C for longer. This product should be stored undiluted. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
General Ignatowicz, Kappler, Marrack et al.: "Identification of two V beta 7-specific viral superantigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 1, pp. 65-71, 1994 (PubMed).

Okada, Holzmann, Guidos et al.: "Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 9, pp. 3473-7, 1990 (PubMed).

Catalog No. ABIN118342

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