T Cell Receptor (TCR) Vb 7 antibody

Antigen: T Cell Receptor (TCR) Vb 7

Clonality: Monoclonal (TR310)

Host: Rat

Reactivity: Mouse (Murine)

Application: Flow Cytometry (FACS)

Catalog no.: ABIN118342

Additional Information

Immunogen: T-cell lymphoma TK1. Spleen cells from immunised mice were fused with cells of the P3-X63 Ag8.3 rat myeloma cell line

Isotype: IgG2b  (Matching secondary antibodies)

Clone: TR310

Specificity: This antibody reacts with the TCR Vb7 bearing T cells. Note that TCR Vb7 may not be present in mouse strains expressing MIS-1a haplotype.

Application Details

Application Notes: Flow cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.2 mg/ml

Buffer: PBS containing 0.09% Sodium Azide

Storage: Store the antibody at 4-8°C for one month or at -20°C for longer. This product should be stored undiluted. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Research Area: Immunology, Receptors, Signaling

Restrictions: For Research Use only

Publications

Publications: Okada, Holzmann, Guidos et al.: "Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 9, pp. 3473-7, 1990 (PubMed).

Ignatowicz, Kappler, Marrack et al.: "Identification of two V beta 7-specific viral superantigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 1, pp. 65-71, 1994 (PubMed).