T Cell Receptor (TCR) Vb 7 antibody (PE)

Antigen: T Cell Receptor (TCR) Vb 7

Clonality: Monoclonal (TR310)

Host: Rat

Reactivity: Mouse (Murine)

Conjugate: PE

Application: Flow Cytometry (FACS)

Catalog no.: ABIN118343

Additional Information

Immunogen: T-cell lymphoma TK1. Spleen cells from immunised mice were fused with cells of the P3-X63 Ag8.3 myeloma cell line

Isotype: IgG2b

Clone: TR310

Specificity: This antibody reacts with the TCR V beta 7 bearing T cells. Note that TCR V beta 7 may not be present in strains expressing MIS-1 haplotype.

Application Details

Application Notes: Flow cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Buffer: PBS containing 0.09% Sodium Azide and 1% Bovine Serum Albumin

Storage: Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf Life: one year from despatch.

Research Area: Immunology, Receptors, Signaling

Restrictions: For Research Use only

Publications

Publications: Okada, Holzmann, Guidos et al.: "Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 9, pp. 3473-7, 1990 (PubMed).

Ignatowicz, Kappler, Marrack et al.: "Identification of two V beta 7-specific viral superantigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 1, pp. 65-71, 1994 (PubMed).