Interferon gamma (IFNG) antibody (Biotin)

Details for Product No. ABIN118370
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Antigen
Synonyms IFG, IFI, Ifg, IFN-g, IFNG2, IFN-gamma, IFN-G
Reactivity
Mouse (Murine)
(332), (158), (81), (28), (20), (13), (11), (11), (7), (7), (6), (5), (4), (4), (3), (2), (1), (1)
Host
Rat
(294), (185), (100), (19), (8), (3), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Biotin
(76), (52), (22), (13), (9), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application
ELISA
(373), (316), (166), (73), (67), (57), (51), (49), (48), (48), (30), (29), (26), (11), (11), (9), (7), (5), (5), (4), (3), (3), (3), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN118370
Quantity 0.2 mg
Price
511.50 $   Plus shipping costs $45.00
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Clone XMG1-2
Isotype IgG1
Specificity This antibody recognises gamma IFN and may be used for the flow cytometric detection of intracellular cytokine.
Purification Affinity chromatography on Protein G
Alternative Name IFNG / Interferon gamma
Background Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.
Alternate names: IFN-gamma, gamma IFN
Gene ID 15978
NCBI Accession NP_032363.1
UniProt P01580
Application Notes Flow cytometry: Membrane permeabilisation is required for this application. ELISA: 0.25ug/ml - 2.0ug/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBs, pH7.4 containing 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Cherwinski, Schumacher, Brown et al.: "Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies." in: The Journal of experimental medicine, Vol. 166, Issue 5, pp. 1229-44, 1987 (PubMed).

Hosts (294), (185), (100), (19), (8), (3), (2), (1)
Reactivities (332), (158), (81), (28), (20), (13), (11), (11), (7), (7), (6), (5), (4), (4), (3), (2), (1), (1)
Applications (373), (316), (166), (73), (67), (57), (51), (49), (48), (48), (30), (29), (26), (11), (11), (9), (7), (5), (5), (4), (3), (3), (3), (1), (1), (1), (1), (1)
Conjugates (76), (52), (22), (13), (9), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Epitopes (11), (10), (5), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
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