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Integrin Alpha2b (CD41) antibody

Details for Product No. ABIN118655, Supplier: Log in to see
Antigen
  • AI172977
  • CD41
  • CD41B
  • GpIIb
  • alphaIIb
  • BDPLT16
  • BDPLT2
  • GP2B
  • GPIIb
  • GT
  • GTA
  • HPA3
Reactivity
Human
292
117
20
10
7
6
5
4
3
2
1
1
1
Host
Mouse
258
93
48
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
44
30
20
10
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
288
69
59
47
44
41
40
25
16
11
10
7
5
3
2
2
2
2
1
1
1
1
1
Supplier
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Immunogen Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Clone PM6-248
Isotype IgG1
Purification Affinity chromatography on Protein G
Alternative Name CD41 / ITGA2B (CD41 Antibody Abstract)
Background CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
Gene ID 9606
UniProt P08514
Application Notes Flow cytometry: 1/100 - 1/200, Use 10 μL of the suggested working dilution to label 100 μL human whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Background publications Michelson, Page, Casey et al.: "An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan." in: The Journal of rheumatology, Vol. 21, Issue 12, pp. 2261-5, 1995 (PubMed).

Hornby, Brown, Wilkinson et al.: "Activation of human platelets by exposure to a monoclonal antibody, PM6/248, to glycoprotein IIb-IIIa." in: British journal of haematology, Vol. 79, Issue 2, pp. 277-85, 1992 (PubMed).