Integrin Alpha2b (CD41) antibody

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Antigen
  • AI172977
  • CD41
  • CD41B
  • GpIIb
  • alphaIIb
  • BDPLT16
  • BDPLT2
  • GP2B
  • GPIIb
  • GT
  • GTA
  • HPA3
  • integrin alpha 2b
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Itga2b
  • ITGA2B
Alternatives
anti-Human Integrin Alpha2b antibody for Biochemical Assay
Reactivity
Human
382
149
28
25
20
18
16
11
7
5
2
2
1
1
1
1
Host
Mouse
344
115
57
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
62
49
39
13
12
12
11
9
9
8
7
6
6
6
5
5
5
5
5
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
399
90
83
78
55
48
48
27
22
15
13
8
7
6
5
2
2
2
2
2
1
1
1
Options
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Immunogen Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Clone PM6-248
Isotype IgG1
Purification Affinity chromatography on Protein G
Alternative Name CD41 / ITGA2B (CD41 Antibody Abstract)
Background CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
Gene ID 9606
UniProt P08514
Pathways Integrin Complex
Application Notes Flow cytometry: 1/100 - 1/200, Use 10 μL of the suggested working dilution to label 100 μL human whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Background publications Michelson, Page, Casey, Trucksess, Love, Milstien, Wilson, Massaquoi, Crofford, Hallett: "An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan." in: The Journal of rheumatology, Vol. 21, Issue 12, pp. 2261-5, 1995 (PubMed).

Hornby, Brown, Wilkinson, Mattock, Authi: "Activation of human platelets by exposure to a monoclonal antibody, PM6/248, to glycoprotein IIb-IIIa." in: British journal of haematology, Vol. 79, Issue 2, pp. 277-85, 1992 (PubMed).