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Integrin Alpha2b (CD41) antibody (FITC)

Details for Product No. ABIN118657, Supplier: Log in to see
Antigen
  • AI172977
  • CD41
  • CD41B
  • GpIIb
  • alphaIIb
  • BDPLT16
  • BDPLT2
  • GP2B
  • GPIIb
  • GT
  • GTA
  • HPA3
  • integrin alpha 2b
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Itga2b
  • ITGA2B
Reactivity
Human
377
146
23
20
19
19
15
7
4
4
1
1
1
1
Host
Mouse
345
117
57
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
64
53
39
12
10
10
9
8
7
7
5
5
5
5
5
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
397
91
76
71
55
51
47
29
22
14
11
7
6
5
3
2
2
2
2
2
1
1
1
1
1
Options
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Immunogen Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells from the SP2/0 mouse myeloma line.
Clone PM6-248
Isotype IgG1
Purification Affinity Chromatography on Protein A.
Alternative Name CD41 / ITGA2B (CD41 Antibody Abstract)
Background CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
Gene ID 9606
UniProt P08514
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Integrin Alpha2b (CD41) antibody (FITC) (ABIN118657) Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD41:FITC (ABIN118...
Background publications Michelson, Page, Casey, Trucksess, Love, Milstien, Wilson, Massaquoi, Crofford, Hallett: "An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan." in: The Journal of rheumatology, Vol. 21, Issue 12, pp. 2261-5, 1995 (PubMed).

Hornby, Brown, Wilkinson, Mattock, Authi: "Activation of human platelets by exposure to a monoclonal antibody, PM6/248, to glycoprotein IIb-IIIa." in: British journal of haematology, Vol. 79, Issue 2, pp. 277-85, 1992 (PubMed).