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Details for Product No. ABIN118755

Integrin beta 3 (ITGB3) antibody

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Antigen
Synonyms BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, INGRB3, integrin
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN118755
Quantity 1 mg
Price
1,006.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen Platelet plasma membrane.
Clone PM6-13
Isotype IgG1
Specificity This antibody recognises a 105kD glycoprotein, which is the integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is alpha receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. This antibody inhibits platelet aggregation and activation induced by thrombin and collagen. Cross reacts with baboon cells (3).
Purification Azide Free
Alternative Name CD61 / ITGB3
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow cytometry: 1/10 – 1/50, use 10 ul of the suggested working dilution to label 106 cells. Immunohistochemistry on frozen sections: recommended positive control tissue: Bone marrow. Immunoprecipitation. Western Blot under non-reducing conditions. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Storage -20 °C
Storage Comment Store at –20°C only. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Hynes: "Integrins: versatility, modulation, and signaling in cell adhesion." in: Cell, Vol. 69, Issue 1, pp. 11-25, 1992 (PubMed).

Michelson, Page, Casey et al.: "An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan." in: The Journal of rheumatology, Vol. 21, Issue 12, pp. 2261-5, 1995 (PubMed).

Alternatives for antigen "Integrin beta 3 (ITGB3)", type "Antibodies"
Hosts (164), (159), (41), (2), (1)
Reactivities (301), (150), (81), (48), (45), (27), (26), (9), (8), (3), (2), (1), (1), (1), (1)
Applications (182), (158), (75), (56), (49), (41), (35), (30), (17), (14), (14), (4), (3), (2), (1)
Conjugates (54), (28), (22), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Epitopes (36), (33), (13), (8), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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