Endoglin antibody (PE)

Catalog No. ABIN118833

Product Details anti-Endoglin Antibody (PE)

Target: Endoglin (ENG)

Reactivity: Human, Horse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises the human CD105 cell surface antigen, a glycoprotein homodimer of 95 kDa subunits.

Purification: Affinity Chromatography on Protein G.

Immunogen: Partially purified cell membrane antigens from fresh leukaemia cells

Clone: SN6

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.0 mL distilled water.

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105 / Endoglin (ENG Products)

Synonyms: ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody

Background: CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.Synonyms: END, ENG, HHT1, ORW, ORW1

Gene ID: 9606

UniProt: P17813