MutS Homolog 6 (E. Coli) (MSH6) antibody

Details for Product No. ABIN118980
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Antigen
Synonyms cb326, wu:fb36c12, LOC100227810, GTBP, GTMBP, HNPCC5, HSAP, p160, AU044881, AW550279, Gtmbp
Reactivity
Human
(117), (31), (22), (14), (13), (12), (1)
Host
Mouse
(63), (46), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Electrophoretic Mobility-Shift Assay (EMSA)
(80), (43), (37), (19), (18), (13), (10), (10), (4), (4), (3), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
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The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN118980
500.50 $
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Immunogen Human MSH6 (GTBP) produced in baculovirus-infected Sf9 cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3X63 Ag8.653 myeloma cell line.
Clone GTBPP1-66-H6
Isotype IgG1
Specificity This antibody recognises MSH6.
Purification Affinity chromatography on Protein G
Alternative Name MSH6
Background MSH6 is a 160kD protein that is a member of the MutS family of DNA mismatch binding proteins. MSH6 is also known as GTBP (G/T binding protein). MSH6 forms a functional heterodimer with MSH2.
Alternate names: DNA mismatch repair protein Msh6, G/T mismatch-binding protein, GTBP, MutS-alpha 160 kDa subunit, p160
Gene ID 2956
NCBI Accession NP_000170
UniProt P52701
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes ELISA. Gel Super Shift Assays: 4ug/20ul. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Palombo, Gallinari, Iaccarino et al.: "GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells." in: Science (New York, N.Y.), Vol. 268, Issue 5219, pp. 1912-4, 1995 (PubMed).

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