Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1) antibody

Antigen: Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1)

Synonyms: SYB1, VAMP-1, DKFZp686H12131, VAMP1, syb1, vamp-1, Syb1

Clonality: Monoclonal (SP10)

Host: Mouse

Reactivity: Cow (Bovine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Catalog no.: ABIN119029

Additional Information

Alternative name: VAMP-1 / Synaptobrevin-1

UniProt: P23763

Cross-Reactivity: Cow (Bovine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis

Isotype: IgM

Clone: SP10

Application Details

Application Notes: Western Blot: 1/5000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 1.0 mg/ml

Purification: Purified

Buffer: PBS, pH7.4 containing 0.09% Sodium Azide

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Restrictions: For Research Use only

Publications

Honer, Dickson, Gleeson et al.: "Regional synaptic pathology in Alzheimer's disease." in: Neurobiology of aging, Vol. 13, Issue 3, pp. 375-82, 1992 (PubMed).

Honer, Kaufmann, Davies: "Characterization of a synaptic antigen of interest in neuropsychiatric illness." in: Biological psychiatry, Vol. 31, Issue 2, pp. 147-58, 1992 (PubMed).

Honer, Kaufmann, Kleinman et al.: "Monoclonal antibodies to study the brain in schizophrenia." in: Brain research, Vol. 500, Issue 1-2, pp. 379-83, 1990 (PubMed).

Honer, Hu, Davies: "Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex." in: Brain research, Vol. 609, Issue 1-2, pp. 9-20, 1993 (PubMed).

Dickson, Davies, Bevona et al.: "Hippocampal sclerosis: a common pathological feature of dementia in very old (> or = 80 years of age) humans." in: Acta neuropathologica, Vol. 88, Issue 3, pp. 212-21, 1995 (PubMed).

Wakabayashi, Honer, Masliah: "Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease." in: Brain research, Vol. 667, Issue 1, pp. 24-32, 1995 (PubMed).

Masliah, Honer, Mallory et al.: "Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus." in: Acta neuropathologica, Vol. 87, Issue 2, pp. 135-42, 1994 (PubMed).

Honer, Beach, Hu et al.: "Hippocampal synaptic pathology in patients with temporal lobe epilepsy." in: Acta neuropathologica, Vol. 87, Issue 2, pp. 202-10, 1994 (PubMed).

Simpson, Chundu, Davies-Hill et al.: "Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease." in: Annals of neurology, Vol. 35, Issue 5, pp. 546-51, 1994 (PubMed).