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Details for Product No. ABIN119185

Cyclin D2 (CCND2) antibody

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Synonyms KIAK0002, cD2, Vin1, Vin-1, C86853, AI256817, BF642806, 2600016F06Rik, ccnd2, si:ch211-240j22.2, CCND2, kiak0002, zgc:162280, LOC100224096
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro))
Pubmed 2 references available
Catalog no. ABIN119185
Quantity 1 mL
533.50 $   Plus shipping costs $45.00
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Immunogen Prokaryotic recombinant protein corresponding to full length cyclin D2.
Clone DCS-3-1
Isotype IgG2a
Specificity This antibody is specific to cyclin D2. Cellular Localization: Nuclear
Purification Ig Fraction
Alternative Name Cyclin D2
Background Overexpession of cyclin D2 leads to acceleration of the G1 phase. The expression of cyclin D2 protein is more restricted than that of cyclin D1.
Alternate names: CCND2, Cyclin-D2
Gene ID 894
NCBI Accession NP_001750.1
UniProt P30279
Research Area Cancer, Cell Cycle
Application Notes Immunohistochemistry on frozen sections: diluted of 1:25-1:50 in an ABC method (30-60 minutes at room temperature) Recommended Positive Control: Breast carcinoma Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer containing sodium azide as preservative.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Lukas, Bartkova, Welcker et al.: "Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types." in: Oncogene, Vol. 10, Issue 11, pp. 2125-34, 1995 (PubMed).

Bartkova, Lukas, Müller et al.: "Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer." in: Cancer research, Vol. 55, Issue 4, pp. 949-56, 1995 (PubMed).

Alternatives for antigen "Cyclin D2 (CCND2)", type "Antibodies"
Hosts (59), (51)
Reactivities (106), (52), (38), (1), (1)
Applications (84), (35), (31), (23), (18), (12), (10), (7), (6), (5), (5), (4), (3), (2), (1), (1), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (5), (4), (4), (3), (3), (3), (1)