Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (Biotin)

Details for Product No. ABIN119270
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Antigen
Reactivity
Human
(52), (38), (19), (2)
Host
Mouse
(94), (15)
Clonality (Clone)
Monoclonal ()
Conjugate
Biotin
(23), (17), (10), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(99), (36), (26), (24), (10), (10), (8), (8), (7), (7), (6), (6), (3)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN119270
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Immunogen Spleen cells from immunised BALB/c mice were fused with cells of the mouse P2X63.Ag8.653 myeloma cell line
Clone B199-2
Isotype IgG2b
Specificity This antibody recognises the CD161 cell surface antigen. Clone B199.2 recognises a similar epitope to the DX9 monoclonal antibody.
Alternative Name CD161 / KLRB1
Background CD161 is expressed by almost all NK cells and with a small subset of CD3+ve T cells. CD161 is a homodimeric cell surface protein, comprising two chains of 40-44kD. Alternate Names: KLRB1, CLEC5B, NKRP1A, CD161, Natural killer cell surface protein P1A, HNKR-P1a, NKR-P1A, C- type lectin domain family 5 member B, , Killer cell lectin-like receptor subfamily B member 1.
UniProt Q12918
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow cytometry: neat - 1/10, use 10 ul of the suggested working dilution to label 10e6 cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
General Bennett, Zatsepina, Zamai et al.: "Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12." in: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1845-56, 1996 (PubMed).

Azzoni, Zatsepina, Abebe et al.: "Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 7, pp. 3493-500, 1998 (PubMed).

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