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TLR4 antibody (PE)

TLR4 Reactivity: Human, Dog, Monkey, Pig, Guinea Pig FACS Host: Mouse Monoclonal HTA125 PE
Catalog No. ABIN119333
  • Target See all TLR4 Antibodies
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Reactivity
    • 179
    • 93
    • 75
    • 37
    • 23
    • 20
    • 19
    • 19
    • 5
    • 2
    • 1
    • 1
    Human, Dog, Monkey, Pig, Guinea Pig
    Host
    • 134
    • 71
    • 5
    • 4
    Mouse
    Clonality
    • 138
    • 76
    Monoclonal
    Conjugate
    • 98
    • 22
    • 20
    • 14
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR4 antibody is conjugated to PE
    Application
    • 155
    • 127
    • 56
    • 50
    • 36
    • 30
    • 27
    • 27
    • 26
    • 25
    • 13
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Rhesus Monkey, Guinea Pig, Porcine and Canine (Dog).
    Purification
    Affinity Chromatography on Protein G
    Immunogen
    Ba/F3 cell line expressing TLR4 (CD284). Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
    Clone
    HTA125
    Isotype
    IgG2a
    Top Product
    Discover our top product TLR4 Primary Antibody
  • Application Notes
    Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells or 100 μL whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1.0 mL distilled water.
    Buffer
    PBS, 0.09 % Sodium Azide, 1 % BSA and 5 % Sucrose
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Prior to and following reconstitution store the antibody at -20 °C.
  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Alternative Name
    CD284 / TLR4 (TLR4 Products)
    Synonyms
    ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
    Background
    TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.Synonyms: Toll-like receptor 4
    NCBI Accession
    NM_138554
    UniProt
    O00206
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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