You are viewing an incomplete version of our website. Please click to reload the website as full version.

Estrogen Receptor alpha antibody (Estrogen Receptor 1)

Details for Product anti-ESR1 Antibody No. ABIN119395, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

ACTGP1, ACT1GP1, HY-psi-gamma-AC6, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, XER, era, esr, esra, nr3a1, ERbeta, xesr-1, ERalpha, xlERalpha1, xlERalpha2, LOC398733, LOC398734, 2610524P08Rik, 9130407C09Rik ... show more
ACTGP1, ACT1GP1, HY-psi-gamma-AC6, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, XER, era, esr, esra, nr3a1, ERbeta, xesr-1, ERalpha, xlERalpha1, xlERalpha2, LOC398733, LOC398734, 2610524P08Rik, 9130407C09Rik, AU019798, Era, M-ERA, MERA-S, MERA-W, ERA, ERAL1A, H-ERA, HERA-A, HERA-B, er, esr1, ER, ESR, ESRA, ESTRR, NR3A1, ER-alpha, Esr, RNESTROR, ERALPHA, ER[a], eralpha, zfER[a], ESR1, AA420328, AU041214, ERa, Estr, Estra, Nr3a1 show less
Show less
(828), (281), (167), (27), (11), (11), (11), (7), (6), (4), (3), (2), (2), (1), (1)
(635), (232), (8), (3), (3)
Clonality (Clone)
Monoclonal ()
This Estrogen Receptor alpha antibody is un-conjugated
(31), (31), (28), (15), (14), (14), (10), (8), (8), (8), (8), (8), (8), (8), (8)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(632), (272), (272), (170), (122), (92), (70), (39), (26), (15), (12), (9), (8), (6), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.5 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Prokaryotic recombinant protein corresponding to the full-length estrogen receptor molecule.
Clone 6F11
Isotype IgG1
Specificity This antibody is specific to estrogen receptor, which is associated with superior prognosis and a better response to endocrine therapy.
Cellular Localization: Nuclear
Purification Supernatant
Alternative Name Estrogen Receptor alpha (ESR1 Antibody Abstract)
Background The nuclei of the estrogen receptor positive cells stain very strongly with this antibody, without any staining in the cytoplasm.Synonyms: ER alpha, ESR, ESR1, Estradiol receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1
Gene ID 2099
NCBI Accession NP_000116
UniProt P03372
Research Area Cancer, Endocrine system, Transcription Factors, Hormones, Receptors
Pathways Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway
Application Notes Immunoprecipitation: 1:50. Western Blot: 1:50 to 1:100. Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1:20 to 1:80 in an ABC method (30 minutes at room temperature) Recommended Positive Control: Breast carcinoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Product cited in: Konwisorz, Springwald, Haselberger et al.: "Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells." in: Endocrine-related cancer, Vol. 17, Issue 1, pp. 147-57, 2010 (PubMed).

Background publications Kumar, Green, Stack et al.: "Functional domains of the human estrogen receptor." in: Cell, Vol. 51, Issue 6, pp. 941-51, 1988 (PubMed).

Pertschuk, Kim, Nayer et al.: "Immunocytochemical estrogen and progestin receptor assays in breast cancer with monoclonal antibodies. Histopathologic, demographic, and biochemical correlations and relationship to endocrine response and survival." in: Cancer, Vol. 66, Issue 8, pp. 1663-70, 1990 (PubMed).

Graham, Jin, Lloyd: "Detection of estrogen receptor in paraffin-embedded sections of breast carcinoma by immunohistochemistry and in situ hybridization." in: The American journal of surgical pathology, Vol. 15, Issue 5, pp. 475-85, 1991 (PubMed).

Bur, Zimarowski, Schnitt et al.: "Estrogen receptor immunohistochemistry in carcinoma in situ of the breast." in: Cancer, Vol. 69, Issue 5, pp. 1174-81, 1992 (PubMed).

Catalog No. ABIN119395
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)