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Details for Product No. ABIN119593

Toll-Like Receptor 2 (TLR2) antibody (PE)

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Antigen
Synonyms TIL4, CD282, Ly105
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
Application
»Alternatives Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN119593
Quantity 100 tests
Price
676.50 $   Plus shipping costs $45.00
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Immunogen CHO cell line transfected with Human TLR2 (CD282). Spleen cells from immunised BALB/c mice were fused with cells of the NSO myeloma cell line.
Clone TLR2-3
Isotype IgG2a
Specificity Recognises toll-like receptor 2 (TLR2).
Purification Affinity Chromatography on Protein G
Alternative Name CD282 / TLR2
Background TLR2 is a 90kD type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.
Alternate names: Toll-like receptor 2
NCBI Accession 9606
UniProt O60603
Research Area Signaling, Immunology, Inflammation
Application Notes Flow Cytometry: Use 10 ul of neat antibody to label 10e6 cells in 100 ul. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 1.0 mL distilled water.
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 0.09% Sodium Azide 1% BSA
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody prior to reconstitution at -20°C. ollowing reconstitution the antibody can be stored at 2-8°C for one month or at -20°C for longer.
Expiry Date 12 months
Background publications Lien, Sellati, Yoshimura et al.: "Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products." in: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33419-25, 1999 (PubMed).

Flo, Halaas, Torp et al.: "Differential expression of Toll-like receptor 2 in human cells." in: Journal of leukocyte biology, Vol. 69, Issue 3, pp. 474-81, 2001 (PubMed).

Alternatives for antigen "Toll-Like Receptor 2 (TLR2)", type "Antibodies"
Hosts (277), (92), (38), (6), (5)
Reactivities (321), (155), (23), (20), (13), (13), (12), (4), (2), (1), (1), (1)
Applications (245), (158), (97), (94), (57), (49), (47), (44), (31), (28), (26), (10), (6), (2), (2), (1), (1), (1)
Conjugates (54), (52), (30), (6), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (25), (14), (8), (6), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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