CD84 Molecule (CD84) antibody

Details for Product No. ABIN119617
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Antigen
Synonyms RGD1564553, A130013D22Rik, CDw84, SLAMF5, LY9B, hCD84, mCD84
Reactivity
Human
(71), (25), (12)
Host
Mouse
(56), (36), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(11), (11), (8), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Functional Studies (Func), Immunoprecipitation (IP), Flow Cytometry (FACS)
(52), (25), (24), (22), (10), (7), (5), (4), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 1 mg
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Catalog No. ABIN119617
1,094.50 $
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Immunogen Mouse pre-B cell line 300.19 transfected with CD84 cDNA. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS-1 myeloma cell line.
Clone CD84-1-21
Isotype IgG1
Specificity This antibody recognises the CD84 cell surface antigen. This antibody has been shown to partially block CD84 homophilic binding.
Purification Affinity chromatography on Protein G
Alternative Name CD84 / SLAMF5
Background CD84 is a highly glycosylated cell surface antigen of 64-82kD. CD84 is predominantly expressed by B lymphocytes, monocytes and macrophages, although lower levels of expression have also been reported on T cells, granulocytes and platelets.
Alternate names: Cell surface antigen MAX.3, Hly9-beta, Leukocyte differentiation antigen CD84, MAX.3, SLAM family member 5, Signaling lymphocytic activation molecule 5
Gene ID 8832
NCBI Accession NP_001171808
UniProt Q9UIB8
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow cytometry: 1/10 - 1/50, use 10 ul of the suggested working dilution to label 10e6 cells. Immunoprecipitation. Functional Assays. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS
Preservative Azide free
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Expiry Date 12 months
Supplier Images
anti-CD84 Molecule (CD84) antibody anti-CD84 Molecule (CD84) antibody
Background publications Martin, Romero, de la Fuente et al.: "CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 7, pp. 3668-76, 2001 (PubMed).

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