CTLA4 antibody
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- Target See all CTLA4 Antibodies
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CTLA4 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognises CD152, also known as cytotoxic-T-lymphocyte antigen-4 (CTLA-4).
- Purification
- Affinity chromatography on Protein G
- Immunogen
- Purified rCTLA-4hIg fusion protein. Spleen cells from immunised Balb/c were fused with cells of the X63-Ag8-653 myeloma cell line.
- Clone
- WKH203
- Isotype
- IgG1
- Top Product
- Discover our top product CTLA4 Primary Antibody
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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody (PE)
CTLA4 Reactivity: Human FACS Host: Mouse Monoclonal BNI3 PE
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-135) antibodyCTLA4 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2F1 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) antibodyCTLA4 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9D2E9 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibodyCTLA4 Reactivity: Human FACS, WB, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 8B3F8 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 41-90) antibodyCTLA4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 52-211) antibodyCTLA4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 75-170) antibodyCTLA4 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 50-78) antibodyCTLA4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB23352 unconjugated
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- Application Notes
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Flow cytometry: 1:10 - 1:20, use 10 μL to label 10^6 cells in 100 μL, membrane permeabilisation is required for this application. ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Alternative Name
- CD152 / CTLA4 (CTLA4 Products)
- Synonyms
- CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
- Background
- CD152 is similar in structure to CD28 and also binds ligands CD80 and CD86. CD152 is expressed by activated T-lymphocytes. Studies suggest that CD152 is also expressed by regulatory T-lymphocytes.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
- Gene ID
- 63835
- NCBI Accession
- NP_113862
- UniProt
- Q62859
- Pathways
- Cancer Immune Checkpoints
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