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Kinase Suppressor of Ras 1 (KSR1) antibody

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Mouse (Murine), Rat (Rattus)
(85), (47), (23)
(94), (6), (4)
Clonality (Clone)
Monoclonal ()
(7), (7), (7), (6), (6), (6), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(84), (57), (25), (12), (12), (10), (3), (2), (2), (1), (1)
Pubmed 2 references available
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Quantity 0.1 mg
Shipping to United States ( )
Immunogen Recombinant human KSR protein
Clone MINT-1-14
Isotype IgG2a
Specificity This antibody recognises the kinase suppressor of Ras (KSR).
Purification Affinity chromatography on Protein G
Alternative Name Kinase Suppressor of Ras 1 (KSR1 Antibody Abstract)
Background KSR was initially considered to be a protein kinase acting in the Ras pathway, but has more recently been demonstrated to act as a scaffold protein, facilitating complex formation between RAF and MEK and ERK.Synonyms: KSR, KSR-1, KSR1
Gene ID 8844
NCBI Accession NP_055053
UniProt Q8IVT5
Application Notes Immunohistochemistry on paraffin (Methacarn fixation recommended) and frozen sections. Western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Kinase Suppressor of Ras 1 (KSR1) antibody (ABIN119637) Western blot of myc-tagged murine KSR expressed in COS cells using rat anti KSR (ABIN...
Background publications Giblett, Lloyd, Light et al.: "Expression of kinase suppressor of Ras in the normal adult and embryonic mouse." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 13, Issue 7, pp. 307-13, 2002 (PubMed).

Morrison: "KSR: a MAPK scaffold of the Ras pathway?" in: Journal of cell science, Vol. 114, Issue Pt 9, pp. 1609-12, 2001 (PubMed).

Catalog No. ABIN119637

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