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Kinase Suppressor of Ras 1 (KSR1) antibody

Antigen

Kinase Suppressor of Ras 1 (KSR1)
Synonyms KSR, RSU2, hb, Ksr, B-KSR1, AW492498, D11Bhm183e, D11Bhm184e, EK3-1, KSR-1, SR3-1, dKsr, l(3)j5E2, DmelCG2899, CG2899
Clonality Monoclonal (MINT-1-14)
Host
Reactivity
Alternatives

Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
2 references available
Catalog no. ABIN119637
Quantity 0.1 mg  (1.0 mg/ml)
Price 429.00 $   Plus shipping costs $45.00
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anti-Kinase Suppressor of Ras 1 (KSR1) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name Kinase suppressor of Ras 1
UniProt Q8IVT5
Immunogen Recombinant human KSR protein
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Isotype IgG2a
Clone MINT-1-14
Description KSR was initially considered to be a protein kinase acting in the Ras pathway, but has more recently been demonstrated to act as a scaffold protein, facilitating complex formation between RAF and MEK and ERK. Alternate Names: KSR.

Application Details
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Application Notes Immunohistochemistry on paraffin (Methacarn fixation recommended) and frozen sections. Western blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Purified
Buffer PBS containing 0.09% Sodium Azide
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Morrison: "KSR: a MAPK scaffold of the Ras pathway?" in: Journal of cell science, Vol. 114, Issue Pt 9, pp. 1609-12, 2001 (PubMed).

Giblett, Lloyd, Light et al.: "Expression of kinase suppressor of Ras in the normal adult and embryonic mouse." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 13, Issue 7, pp. 307-13, 2002 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Kinase Suppressor of Ras 1 (KSR1)", type "Antibodies"
Hosts Rabbit (44), Rat (2), Mouse (1)
Reactivities Human (45), Mouse (Murine) (28), Rat (Rattus) (25), Chicken (19), Cow (Bovine) (19), Dog (Canine) (19), Horse (Equine) (19), Pig (Porcine) (19)
Applications Immunofluorescence (IF) (25), Western Blotting (WB) (25), ELISA (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunohistochemistry (IHC) (5), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (3), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer392 (6), C-Term (3), N-Term (2), AA 118-248 (1), AA 214-226 (1), Internal Region (1), N-Term, Ala7 (1), N-Term,Glu173 (1), pSer404 (1), pSer44 (1)