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Details for Product No. ABIN119637

Kinase Suppressor of Ras 1 (KSR1) antibody

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Antigen
Synonyms KSR, RSU2, hb, Ksr, B-KSR1, AW492498, D11Bhm183e, D11Bhm184e, CG2899, Dmel\\CG2899, EK3-1, KSR-1, Ksr-1, SR3-1, dKsr, l(3)j5E2
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus)
Host
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Pubmed 2 references available
Catalog no. ABIN119637
Quantity 0.1 mg
Price
456.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant human KSR protein
Clone MINT-1-14
Isotype IgG2a
Specificity This antibody recognises the kinase suppressor of Ras (KSR).
Purification Affinity chromatography on Protein G
Alternative Name Kinase suppressor of Ras 1
Background KSR was initially considered to be a protein kinase acting in the Ras pathway, but has more recently been demonstrated to act as a scaffold protein, facilitating complex formation between RAF and MEK and ERK.
Alternate names: KSR, KSR-1, KSR1
Gene ID 8844
NCBI Accession NP_055053.1
UniProt Q8IVT5
Application Notes Immunohistochemistry on paraffin (Methacarn fixation recommended) and frozen sections. Western blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Giblett, Lloyd, Light et al.: "Expression of kinase suppressor of Ras in the normal adult and embryonic mouse." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 13, Issue 7, pp. 307-13, 2002 (PubMed).

Morrison: "KSR: a MAPK scaffold of the Ras pathway?" in: Journal of cell science, Vol. 114, Issue Pt 9, pp. 1609-12, 2001 (PubMed).

Alternatives for antigen "Kinase Suppressor of Ras 1 (KSR1)", type "Antibodies"
Hosts (54), (4), (3)
Reactivities (58), (39), (26), (12), (12), (12), (12)
Applications (42), (23), (20), (14), (13), (7), (4), (2), (2)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (17), (12), (8), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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