CCR5 antibody (PE)

Catalog No. ABIN119679

Product Details anti-CCR5 Antibody (PE)

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This CCR5 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises the CD195 cell surface antigen, a 45 kDa glycoprotein also known as CCR5.

Purification: Affinity chromatography on Protein G

Immunogen: CHO cells transfected with human CCR5. Spleen cells from immunised rats were fused with cell of the rat Y3 myeloma cell line.

Clone: HEK-1-85a

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: Neat - 1/5, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1 mL distilled water

Buffer: PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store the antibody at -20 °C.

Target Details for CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Alternative Name: CD195 / CCR5 (CCR5 Products)

Synonyms: CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody

Background: CD195 acts as a receptor for a number of chemokines including RANTES and eotaxin and also serves as a coreceptor for the entry of HIV into cells. CD195 is expressed by a subset of T lymphocytes and by monocytes.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor

Gene ID: 1234

NCBI Accession: NP_000570

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size