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CD177 antibody (FITC)

CD177 Reactivity: Human FACS Host: Mouse Monoclonal MEM-166 FITC
Catalog No. ABIN119766
  • Target See all CD177 Antibodies
    CD177 (CD177 Molecule (CD177))
    Reactivity
    • 49
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    Human
    Host
    • 33
    • 21
    Mouse
    Clonality
    • 35
    • 19
    Monoclonal
    Conjugate
    • 28
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD177 antibody is conjugated to FITC
    Application
    • 31
    • 21
    • 13
    • 10
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody recognises human CD177 (neutrophil glycoprotein NB1). The neutrophil NB1 antigen is expressed by 97 % of the caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN). Antibody reactivity and working conditions may vary between species.
    Purification
    Protein G affinity chromatography
    Clone
    MEM-166
    Isotype
    IgG1
    Top Product
    Discover our top product CD177 Primary Antibody
  • Application Notes
    Flow cytometry (use 10 μL of neat - 1/10 diluted antibody to label 10^6 cells in 100 μL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS with 0.09 % sodium azide as preservative and 1 % BSA as stabelizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2-8 °C for one month or (in small aliquots) at -20 °C for longer.
  • Target
    CD177 (CD177 Molecule (CD177))
    Alternative Name
    CD177 (CD177 Products)
    Synonyms
    HNA-2a antibody, HNA2A antibody, NB1 antibody, NB1 GP antibody, PRV-1 antibody, PRV1 antibody, RGD1562941 antibody, CD177 antibody, MGC157159 antibody, 1190003K14Rik antibody, Pdp3 antibody, CD177 molecule antibody, CD177 antigen antibody, CD177 antibody, Cd177 antibody
    Background
    Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97 % of the caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1
    Gene ID
    57126
    NCBI Accession
    NP_065139
    UniProt
    Q8N6Q3
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