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CD177 antibody

CD177 Reactivity: Human, Primate WB, FACS, IP Host: Mouse Monoclonal MEM-166 unconjugated
Catalog No. ABIN119768
  • Target See all CD177 Antibodies
    CD177 (CD177 Molecule (CD177))
    Reactivity
    • 48
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    Human, Primate
    Host
    • 33
    • 20
    Mouse
    Clonality
    • 35
    • 18
    Monoclonal
    Conjugate
    • 27
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD177 antibody is un-conjugated
    Application
    • 30
    • 20
    • 12
    • 10
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificity
    This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Non-Human Primates.
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    Human Granulocytes
    Clone
    MEM-166
    Isotype
    IgG1
    Top Product
    Discover our top product CD177 Primary Antibody
  • Application Notes
    Flow cytometry. Immunoprecipitation. Western Blot under non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH ~7.4, 15 mM Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated thawing and freezing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the original vial at 2-8 °C, stock solution or aliquots thereof at -20 °C.
  • Target
    CD177 (CD177 Molecule (CD177))
    Alternative Name
    CD177 (CD177 Products)
    Synonyms
    HNA-2a antibody, HNA2A antibody, NB1 antibody, NB1 GP antibody, PRV-1 antibody, PRV1 antibody, RGD1562941 antibody, CD177 antibody, MGC157159 antibody, 1190003K14Rik antibody, Pdp3 antibody, CD177 molecule antibody, CD177 antigen antibody, CD177 antibody, Cd177 antibody
    Background
    CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31(PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1
    Gene ID
    57126
    NCBI Accession
    NP_065139
    UniProt
    Q8N6Q3
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