This antibody recognises CD150, also known as signalling lymphocyte activation molecule (SLAM). Clone 9D1 is reported to have functional activity. We recommend the use of SM2026A for this purpose. This antibody is routinely tested on mouse thymocytes.
Purification
Affinity chromatography on Protein G
Immunogen
CHO cells stably transfected with mouse CD150. Spleen cells from immunised rats were fused with cells of a myeloma cell line.
CD150 antibody, SLAM antibody, SLAMF1 antibody, 4933415F16 antibody, AA177906 antibody, CDw150 antibody, ESTM51 antibody, IPO-3 antibody, Slam antibody, RGD1560634 antibody, signaling lymphocytic activation molecule family member 1 antibody, SLAMF1 antibody, Slamf1 antibody
Background
Murine CD150 is a 75 kDa cell surface glycoprotein that is expressed on T-cells and B-cells, and has been shown to be upregulated on activated T-cells and stimulated macrophages. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T-cells and Bcells.Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam