ICAM2 antibody

Catalog No. ABIN120004

Product Details anti-ICAM2 Antibody

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ICAM2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Specificity: This antibody recognises intercellular adhesion molecule-2 (ICAM-2), also known as CD102. Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1.

Purification: Affinity chromatography on Protein G

Endotoxin Level: Low Endotoxin

Immunogen: COS cells transfected with murine ICAM-2. Spleen cells from immunised Lewis rats were fused with cells of the Mouse P3X63Ag8.653 myeloma cell line.

Clone: MIC2-4 (3C4)

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry: 1/50 - 1/200, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Ship at 2 - 8 °C.

Target Details for ICAM2

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Alternative Name: CD102 / ICAM2 (ICAM2 Products)

Synonyms: ICAM2 antibody, CD102 antibody, Icam-2 antibody, Ly-60 antibody, intercellular adhesion molecule 2 antibody, LOC506088 antibody, ICAM2 antibody, LOC616254 antibody, LOC100140873 antibody, Icam2 antibody

Background: Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation.Synonyms: ICAM-2, Intercellular adhesion molecule 2

Gene ID: 3384

NCBI Accession: NP_000864

UniProt: P13598