CCL7 antibody

Catalog No. ABIN120075

Product Details anti-CCL7 Antibody

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL7 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificity: This antibody specifically recognises MCP-3, also known as CCL7. No cross reactivity is observed with MCP-1, MCP-2 or other structurally related chemokines.

Purification: Affinity chromatography on Protein A

Immunogen: Recombinant human MCP-3 (Macrophage Chemoattractant Protein-3) Spleen cells from immunised C3H/HeJ mice were fused with cells of a mouse myeloma cell line.

Clone: H-mcp-3

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/1000. Functional Assays: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.5 mL distilled water. Note: Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently vortexed after reconstitution and microcentrifuged before use.

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Preservative: Azide free

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: MCP3 / CCL7 (CCL7 Products)

Synonyms: CCL7 antibody, FIC antibody, MARC antibody, MCP-3 antibody, MCP3 antibody, NC28 antibody, SCYA6 antibody, SCYA7 antibody, Scya7 antibody, fic antibody, marc antibody, mcp3 antibody, C-C motif chemokine ligand 7 antibody, chemokine (C-C motif) ligand 7 antibody, CCL7 antibody, Ccl7 antibody

Background: This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7

Gene ID: 6354

NCBI Accession: NP_006264

UniProt: P80098