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ICAM2 antibody (Intercellular Adhesion Molecule 2) (FITC)

Details for Product anti-ICAM2 Antibody No. ABIN120195, Supplier: Log in to see
Antigen
  • ICAM2
  • CD102
  • Icam-2
  • Ly-60
Reactivity
Human
160
119
22
Host
Mouse
90
86
86
2
Clonality (Clone)
Monoclonal ()
Conjugate
This ICAM2 antibody is conjugated to FITC
30
23
18
5
5
3
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
182
86
77
56
51
32
24
15
11
6
4
4
4
3
3
2
2
1
1
1
Supplier
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Immunogen Transfected COS cells expressing ICAM-2 cDNA. Cells from immunised BALB/c mice were fused with cells of the Murine P3X63Ag.653 myeloma cell line.
Clone CBRIC2-2
Isotype IgG2a
Specificity This antibody recognises CD102, also known as intercellular adhesion molecule-2 (ICAM-2). Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA-1. We recommend the use of SM2223LE for this purpose.
Purification Affinity Chromatography on Protein G.
Alternative Name CD102 / ICAM2 (ICAM2 Antibody Abstract)
Background CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD18 (LFA-1). Reports suggest that the CD102 may play a role in lymphocyte re-circulation and T-cell activation.Synonyms: ICAM-2, Intercellular adhesion molecule 2
Gene ID 3384
NCBI Accession NP_000864
UniProt P13598
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry (Neat-1/10): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-ICAM2 antibody (Intercellular Adhesion Molecule 2)  (FITC) (ABIN120195) Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD102: FITC (ABIN1...
Background publications Diacovo, deFougerolles, Bainton et al.: "A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2." in: The Journal of clinical investigation, Vol. 94, Issue 3, pp. 1243-51, 1994 (PubMed).

de Fougerolles, Stacker, Schwarting et al.: "Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1." in: The Journal of experimental medicine, Vol. 174, Issue 1, pp. 253-67, 1991 (PubMed).