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Intercellular Adhesion Molecule 2 (ICAM2) antibody

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Synonyms ICAM2, CD102, Icam-2, Ly-60
(163), (120), (23)
(90), (88), (87), (2)
Clonality (Clone)
Monoclonal ()
(42), (28), (26), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
(183), (89), (77), (56), (52), (31), (23), (15), (11), (6), (6), (6), (4), (3), (3), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 0.2 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Transfected COS cells expressing ICAM-2 cDNA. Cells from immunised BALB/c mice were fused with cells of the Murine P3X63Ag.653 myeloma cell line.
Clone CBRIC2-2
Isotype IgG2a
Specificity This antibody recognises CD102, also known as intercellular adhesion molecule-2 (ICAM-2). Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA-1.
Purification Affinity chromatography on Protein G
Endotoxin Level Low Endotoxin
Alternative Name CD102 / ICAM2 (ICAM2 Antibody Abstract)
Background CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD18 (LFA-1). Reports suggest that the CD102 may play a role in lymphocyte re-circulation and T-cell activation.Synonyms: ICAM-2, Intercellular adhesion molecule 2
Gene ID 3384
NCBI Accession NP_000864
UniProt P13598
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
Supplier Images
Flow Cytometry (FACS) image for anti-Intercellular Adhesion Molecule 2 (ICAM2) antibody (ABIN120196) Stainig of human peripheral blood lymphocytes probed with MOUSE ANTI HUMAN CD102: LOW...
Background publications Diacovo, deFougerolles, Bainton et al.: "A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2." in: The Journal of clinical investigation, Vol. 94, Issue 3, pp. 1243-51, 1994 (PubMed).

de Fougerolles, Stacker, Schwarting et al.: "Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1." in: The Journal of experimental medicine, Vol. 174, Issue 1, pp. 253-67, 1991 (PubMed).

Catalog No. ABIN120196
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