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Intercellular Adhesion Molecule 2 (ICAM2) antibody

Details for Product No. ABIN120196, Supplier: Login to see
Antigen
  • ICAM2
  • CD102
  • Icam-2
  • Ly-60
Reactivity
Human
163
120
23
Host
Mouse
90
88
87
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
42
28
26
5
5
3
2
2
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
183
89
77
56
52
31
23
15
11
6
6
6
4
3
3
2
2
1
1
1
Supplier
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Available images

Immunogen Transfected COS cells expressing ICAM-2 cDNA. Cells from immunised BALB/c mice were fused with cells of the Murine P3X63Ag.653 myeloma cell line.
Clone CBRIC2-2
Isotype IgG2a
Specificity This antibody recognises CD102, also known as intercellular adhesion molecule-2 (ICAM-2). Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA-1.
Purification Affinity chromatography on Protein G
Endotoxin Level Low Endotoxin
Alternative Name CD102 / ICAM2 (ICAM2 Antibody Abstract)
Background CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD18 (LFA-1). Reports suggest that the CD102 may play a role in lymphocyte re-circulation and T-cell activation.Synonyms: ICAM-2, Intercellular adhesion molecule 2
Gene ID 3384
NCBI Accession NP_000864
UniProt P13598
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Flow Cytometry: 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
Supplier Images
Flow Cytometry (FACS) image for anti-Intercellular Adhesion Molecule 2 (ICAM2) antibody (ABIN120196) Stainig of human peripheral blood lymphocytes probed with MOUSE ANTI HUMAN CD102: LOW...
Background publications Diacovo, deFougerolles, Bainton et al.: "A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2." in: The Journal of clinical investigation, Vol. 94, Issue 3, pp. 1243-51, 1994 (PubMed).

de Fougerolles, Stacker, Schwarting et al.: "Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1." in: The Journal of experimental medicine, Vol. 174, Issue 1, pp. 253-67, 1991 (PubMed).