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Antibodies
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anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibody (PE)
Chemokine (C-C Motif) Receptor 7 (CCR7) antibody (PE)
| Antigen |
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| Synonyms |
BLR2, EBI1, CD197, CDw197, CMKBR7, Ebi1h, Cdw197, Cmkbr7, MGC108519, CCR7, MGC165629, zgc:165629 |
| Clonality |
Monoclonal (4B12) |
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Host
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Reactivity
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Conjugate
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Application
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| Catalog no. |
ABIN120213 |
| Quantity |
100 Tests (0.1 mg/ml) |
| Price |
460.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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CD197 / CCR7
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Swiss-Prot
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P47774
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Immunogen
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CCR7 rat basophilic leukaemia (RBL)-2H3 transfectants. Spleen cells from immunised Lou/c rats were fused with cells of the mouse X63.Ag8.653 myeloma cell line
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Isotype
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IgG2a
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Clone
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4B12
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Description
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CD197 is a 43kD member of the G-protein coupled receptor family, which is commonly known as chemokine receptor 7 (CCR7). In mice, CD197 is expressed on most naive T cells, a subset of memory T cells, B cells, mature dendritic cells, NK cells, a subset of thymocytes and CD34+ macrophage progenitor cells. CD197 is a functional receptor for chemokines CCL21 and CCL19. The receptor plays an important role in regulating the trafficking and homing of lymphocytes and dendritic cells to secondary lymphoid organs. Alternate Names: CCR7.
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Specificity
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This antibody recognises CD197. Clone 4B12 does not block the binding of the ligand to CD197.
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Application Notes
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Flow Cytometry: For optimal staining in flow cytometry, incubations should be performed at 37oC for 30 minutes, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.1 mg/ml
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Buffer
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PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
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Storage
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Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf Life: one year from despatch.Reconstitution: Restore with 1.0 ml distilled water.
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Research Area
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CD Antigens, Surface Receptors of Immune Cells
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Restrictions
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For Research Use only
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Alternatives for antigen "Chemokine (C-C Motif) Receptor 7 (CCR7)", type "Antibodies"
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Hosts
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Rabbit (9), Rat (3), Mouse (1)
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Reactivities
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Human (10), Mouse (Murine) (5), Rat (Rattus) (2)
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Applications
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Flow Cytometry (FACS) (4), Immunoprecipitation (IP) (3), Western Blotting (WB) (3), Enzyme Immunoassay (EIA) (2), Immunofluorescence (IF) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Conjugates
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Biotin (1)
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Epitopes
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C-Term (1)
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Alternatives 
