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2B4 antibody

CD244 Reactivity: Human FACS, IP Host: Mouse Monoclonal 2B4-69 unconjugated
Catalog No. ABIN120312
  • Target See all 2B4 (CD244) Antibodies
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    Reactivity
    • 60
    • 25
    • 12
    Human
    Host
    • 53
    • 7
    • 4
    Mouse
    Clonality
    • 55
    • 9
    Monoclonal
    Conjugate
    • 27
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This 2B4 antibody is un-conjugated
    Application
    • 56
    • 26
    • 26
    • 24
    • 20
    • 9
    • 6
    • 6
    • 5
    • 5
    • 4
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificity
    This antibody is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
    Purification
    Affinity Chromatography on Protein G.
    Immunogen
    CD244 Fusion protein. Spleen cells from immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.
    Clone
    2B4-69
    Isotype
    IgG1
    Top Product
    Discover our top product CD244 Primary Antibody
  • Application Notes
    Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 106 cells in 100 μL. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    Alternative Name
    CD244 (CD244 Products)
    Synonyms
    CD244 antibody, 2B4 antibody, NAIL antibody, NKR2B4 antibody, Nmrk antibody, SLAMF4 antibody, C9.1 antibody, F730046O15Rik antibody, Ly90 antibody, CD244 molecule antibody, CD244 natural killer cell receptor 2B4 antibody, CD244 antibody, Cd244 antibody
    Background
    The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4
    Gene ID
    51744
    NCBI Accession
    NP_001160135
    UniProt
    Q9BZW8
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