CD41, CD61 antibody

Catalog No. ABIN120593

Product Details anti-CD41, CD61 Antibody

Target: CD41, CD61 (CD41,CD61)

Reactivity: Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD41, CD61 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Affinity Chromatography on Protein A .

Immunogen: Bovine trombocytes

Clone: IVA30

Isotype: IgG2

Application Details

Application Notes: Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Frozen Sections. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM Sodium Azide as preservative, approx. pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CD41, CD61

Target: CD41, CD61 (CD41,CD61)

Abstract: CD41, CD61 Products

Background: CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIba (heavy chain, 120 kDa) and GPIIbb (light chain, 23 kDa). CD61 non-covalently associates with CD41. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes, the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb

UniProt: P08514