Mouse anti-Human IgA (Chain alpha) Antibody

Catalog No. ABIN120642

Product Details

Target: IgA

Binding Specificity: Chain alpha

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Precipitation methods and Ion Exchange Chromatography.

Immunogen: Purified human IgA

Clone: AD3

Isotype: IgG1

Application Details

Application Notes: ELISA.

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: 20 mM Tris/HCl, pH ~7.4 with 15 mM Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4-8 °C for up to one month or at -20 °C for longer.

Target Details

Target: IgA

Abstract: IgA Products

Target Type: Antibody

Background: Immunoglobulin A (IgA) is the major immunoglobulin class in body secretions that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. Its serum concentration is approximately 0.2 g/l and biological survival (T1/2 in plasma) 6 days. Plasma IgA is predominantly monomeric (160 kDa) and of the IgA1 subclass, and is mostly produced in the bone marrow. Over half of IgA produced by the intestinal lamina propria plasmocytes is in oligomeric form and 35 % of it is IgA2.Synonyms: Human Immunoglobulin A

Molecular Weight: 160 kDa