CD59 antibody
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- Target See all CD59 Antibodies
- CD59
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Reactivity
- Human, Pig
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD59 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificity
- The antibody MEM-129 reacts with CD59 (Protectin).
- Purification
- Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.
- Purity
- > 95 % (by SDS-PAGE).
- Immunogen
- Human peripheral blood lymphocytes
- Clone
- MEM-129
- Isotype
- IgM
- Top Product
- Discover our top product CD59 Primary Antibody
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anti-CD59 (CD59) (AA 31-111) antibody
CD59 Reactivity: Human FACS, WB, IHC, ELISA, ICC Host: Mouse Monoclonal 8D2B8 unconjugated
anti-CD59 (CD59) (AA 74-110) antibodyCD59 Reactivity: Human FACS, WB, IF, IHC (p) Host: Rabbit Polyclonal RB56691 unconjugated
anti-CD59 (CD59) antibodyCD59 Reactivity: Human FACS, IP, IHC (p) Host: Mouse Monoclonal MEM-43 unconjugated
anti-CD59 (CD59) antibodyCD59 Reactivity: Human, Mouse FACS, WB, IP, IHC (p) Host: Mouse Monoclonal MEM-43-5 unconjugated
anti-CD59 (CD59) (AA 31-111) antibodyCD59 Reactivity: Human FACS, WB, IHC, ELISA, IF/ICC Host: Mouse Monoclonal unconjugated
anti-CD59 (CD59) (AA 23-105) antibodyCD59 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD59 (CD59) (AA 1-128) antibodyCD59 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3G6 unconjugated
anti-CD59 (CD59) (AA 26-102) antibodyCD59 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-CD59 (CD59) (AA 52-100) antibodyCD59 Reactivity: Human FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD59 (CD59) antibody (Biotin)CD59 Reactivity: Human FACS, IP, IHC (p) Host: Mouse Monoclonal MEM-43 Biotin
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- Application Notes
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Flow Cytometry. Functional Studies (The antibody activates T-cells).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
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Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CD59
- Alternative Name
- CD59 (CD59 Products)
- Synonyms
- 16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
- Background
- CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
- Gene ID
- 966
- UniProt
- P13987
- Pathways
- Complement System
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